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Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

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Three carcinomas in one eyelid.

Katherine M Whipple¹, Peter N Lombard, Sang Rog Oh

¹Division of Ophthalmic Plastic and Reconstructive Surgery, Department of Ophthalmology, Shiley Eye Center, University of California, San Diego, 9415 Campus Point Drive, 0946, La Jolla, CA 92093-0946, U.S.A. whipplekatherine@yahoo.com

Ophthalmic Plastic and Reconstructive Surgery

|September 11, 2010

Summary

A 90-year-old woman developed two eyelid tumors: Merkel cell carcinoma and squamous cell carcinoma. This highlights the need for thorough pathology in eyelid lesion evaluation.

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Area of Science:

Dermatology
Ophthalmology
Oncology

Background:

Eyelid tumors can present as multiple lesions.
Prior history of skin cancer does not preclude new, distinct malignancies.

Observation:

A 90-year-old female presented with two distinct masses on her right lower eyelid.
One mass was diagnosed as Merkel cell carcinoma, and the other as invasive squamous cell carcinoma.

Findings:

Excisional biopsy confirmed the presence of two independent eyelid malignancies.
The patient had a preceding diagnosis of basal cell carcinoma on the same eyelid.

Implications:

This case underscores the critical importance of comprehensive histopathological examination for all eyelid lesions.
Even with a history of prior skin cancer, new eyelid masses require full diagnostic evaluation to identify potentially aggressive or distinct neoplasms.
Accurate diagnosis is essential for appropriate treatment planning and patient management of eyelid cancers.