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Updated: Jun 8, 2026

Three-Dimensional Cephalometric Landmark Annotation Demonstration on Human Cone Beam Computed Tomography Scans
Published on: September 8, 2023
Using superimposition of 3-dimensional cone-beam computed tomography images with surface-based registration in
Kiyoshi Tai1, Jae Hyun Park, Katsuaki Mishima
1Arizona School of Dentistry & Oral Health, A. T. Still University, Mesa, AZ 85206, USA.
Objective:
The purpose of this research was to evaluate a new method of superimposing detailed cone-beam computed tomography (CBCT) images.
Materials And Methods:
This study used 5 different software programs to transform the digital imaging and communication in medicine (DICOM) data from CBCT image into polygon data. The data conversion errors from different software programs were verified by the poly-acetal ball test and the dry skull test. The iterative closest point (ICP) method was used for precise superimposition. To evaluate changes related to growth, three different domains were superimposed in order to investigate appropriate areas for evaluation by the ICP method.
Results:
The ICP method in the cranial base (excluding the peripheral zone) was indicated as the most reliable surface in this research. There were no measurement errors in converting the image data between software programs.
Conclusion:
The ICP method in the cranial base (excluding the peripheral zone) is one of the most accurate methods for superimposition when the mandibular rotation or displacement has not occurred during growth or treatment. This 3-dimensional (3D) superimposition technique can be used for a valid and reproducible assessment of treatment outcomes for growing subjects. This method is considered to be of clinical value because of the manageability and 3D accuracy of the data comparison with multi planar reconstruction (MPR) images.
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