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Related Experiment Video

Updated: Jun 8, 2026

High-throughput Protein Expression Generator Using a Microfluidic Platform
09:26

High-throughput Protein Expression Generator Using a Microfluidic Platform

Published on: August 23, 2012

Next generation microfluidic platforms for high-throughput protein biochemistry.

Sebastian J Maerkl1

  • 1Institute of Bioengineering, School of Engineering, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland. sebastian.maerkl@epfl.ch

Current Opinion in Biotechnology
|September 14, 2010
PubMed
Summary

High-throughput protein synthesis and characterization methods are emerging, integrating gene synthesis and microfluidics. These advances promise to revitalize protein biochemistry within the field of high-throughput genomics.

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Area of Science:

  • Biochemistry
  • Molecular Biology
  • Systems Biology

Background:

  • DNA technologies have advanced rapidly, transforming life sciences.
  • Protein technologies lag due to proteins' complex physical properties compared to DNA.
  • Recent progress is making high-throughput protein biochemistry relevant for systems biology.

Purpose of the Study:

  • To review methods for high-throughput in situ protein synthesis and characterization.
  • To discuss the integration of these protein methods with microfluidic devices.
  • To highlight the future impact on protein biochemistry in the era of high-throughput genomics.

Main Methods:

  • Review of existing literature on high-throughput protein synthesis.
  • Discussion of in situ protein characterization techniques.

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Related Experiment Videos

Last Updated: Jun 8, 2026

High-throughput Protein Expression Generator Using a Microfluidic Platform
09:26

High-throughput Protein Expression Generator Using a Microfluidic Platform

Published on: August 23, 2012

Digital Microfluidics for Automated Proteomic Processing
10:55

Digital Microfluidics for Automated Proteomic Processing

Published on: November 6, 2009

A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells
15:41

A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells

Published on: October 15, 2013

  • Integration strategies with microfluidic platforms.

    • Main Results:

    • Technological advancements are increasing the throughput of protein biochemistry.
    • Microfluidic devices offer a platform for integrated protein synthesis and analysis.
    • Gene synthesis combined with microfluidics enables efficient protein production.

    Conclusions:

    • High-throughput protein biochemistry is poised for a resurgence.
    • Integration of gene synthesis and microfluidics will drive progress.
    • These advancements will complement high-throughput genomics by enhancing protein analysis.