Related Experiment Video
Updated: Jun 8, 2026

Analysis of HBV-Specific CD4 T-cell Responses and Identification of HLA-DR-Restricted CD4 T-Cell Epitopes Based on a Peptide Matrix
Published on: October 20, 2021
Efficacy of a single dose hepatitis B depot vaccine
Lisa D MacDonald1, Antar Fuentes-Ortega, Leeladhar Sammatur
1ImmunoVaccine Technologies Inc., 1721 Lower Water St. Halifax, Nova Scotia, Canada.
Abstract:
A single dose formulation of a novel hepatitis B vaccine, consisting of an adjuvant emulsion of liposomes in oil was produced at a manufacturing scale and delivered to rabbits. This single dose vaccine generated a significantly higher antibody response than two doses of an alum-adjuvanted control vaccine in the short term, and was as effective as three doses of the control vaccine in the long term.
More Related Videos
Related Concept Videos
Hepatitis
Dose-Response Relationship: Potency and Efficacy
Viral Hepatitis I: Introduction

