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Updated: Jun 8, 2026

Preparation of Meiotic Chromosome Spreads from Mouse Oocytes for Assessment of Synapsis and Recombination
Published on: July 18, 2025
Female meiosis: coming unglued with age
1School for Molecular Biosciences, Washington State University, WA 99164, USA. pathunt@wsu.edu
Abstract:
Chromosome abnormalities in humans are strikingly associated with increasing maternal age. Studies in mice implicate loss of chromosome cohesion as an important cause of age-related meiotic errors in the oocyte.
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