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Related Concept Videos

Bootstrapping01:24

Bootstrapping

The term "bootstrap" originated in the 19th century as a metaphor for self-improvement or achieving something independently, without external assistance. This concept extends to statistical bootstrapping, a self-contained method for estimating population parameters through resampling, even though it can be computationally intensive. Developed by the American statistician Dr. Bradley Efron in 1979, bootstrapping provides a robust way to perform inference when the original sample size is small or...
Propagation of Uncertainty from Random Error00:59

Propagation of Uncertainty from Random Error

An experiment often consists of more than a single step. In this case, measurements at each step give rise to uncertainty. Because the measurements occur in successive steps, the uncertainty in one step necessarily contributes to that in the subsequent step. As we perform statistical analysis on these types of experiments, we must learn to account for the propagation of uncertainty from one step to the next. The propagation of uncertainty depends on the type of arithmetic operation performed on...
Propagation of Uncertainty from Systematic Error01:10

Propagation of Uncertainty from Systematic Error

The atomic mass of an element varies due to the relative ratio of its isotopes. A sample's relative proportion of oxygen isotopes influences its average atomic mass. For instance, if we were to measure the atomic mass of oxygen from a sample, the mass would be a weighted average of the isotopic masses of oxygen in that sample. Since a single sample is not likely to perfectly reflect the true atomic mass of oxygen for all the molecules of oxygen on Earth, the mass we obtain from this particular...
Uncertainty: Confidence Intervals00:54

Uncertainty: Confidence Intervals

The confidence interval is the range of values around the mean that contains the true mean. It is expressed as a probability percentage. The interpretation of a 95% confidence interval, for instance, is that the statistician is 95% confident that the true mean falls within the interval. The upper and lower limits of this range are known as confidence limits. The confidence limits for the true mean are estimated from the sample's mean, the standard deviation, and the statistical factor 't,' or...
Uncertainty: Overview00:59

Uncertainty: Overview

In analytical chemistry, we often perform repetitive measurements to detect and minimize inaccuracies caused by both determinate and indeterminate errors. Despite the cares we take, the presence of random errors means that repeated measurements almost never have exactly the same magnitude. The collective difference between these measurements - observed values - and the estimated or expected value is called uncertainty. Uncertainty is conventionally written after the estimated or expected value.
Uncertainty in Measurement: Accuracy and Precision03:37

Uncertainty in Measurement: Accuracy and Precision

Scientists typically make repeated measurements of a quantity to ensure the quality of their findings and to evaluate both the precision and the accuracy of their results. Measurements are said to be precise if they yield very similar results when repeated in the same manner. A measurement is considered accurate if it yields a result that is very close to the true or the accepted value. Precise values agree with each other; accurate values agree with a true value.

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Related Experiment Video

Updated: Jun 8, 2026

Split Point Analysis and Uncertainty Quantification of Thermal-Optical Organic/Elemental Carbon Measurements
10:22

Split Point Analysis and Uncertainty Quantification of Thermal-Optical Organic/Elemental Carbon Measurements

Published on: September 7, 2019

Standard Error Computations for Uncertainty Quantification in Inverse Problems: Asymptotic Theory vs. Bootstrapping.

H T Banks1, Kathleen Holm, Danielle Robbins

  • 1Center for Research in Scientific Computation and Center for Quantitative Sciences in Biomedicine North Carolina State University Raleigh, NC 27695-8212.

Mathematical and Computer Modelling
|September 14, 2010
PubMed
Summary
This summary is machine-generated.

This study compares bootstrapping and asymptotic theory for uncertainty quantification in nonlinear dynamical systems. Asymptotic theory offers faster computation and more reliable confidence intervals for parameter estimation.

Related Experiment Videos

Last Updated: Jun 8, 2026

Split Point Analysis and Uncertainty Quantification of Thermal-Optical Organic/Elemental Carbon Measurements
10:22

Split Point Analysis and Uncertainty Quantification of Thermal-Optical Organic/Elemental Carbon Measurements

Published on: September 7, 2019

Area of Science:

  • Computational science
  • Dynamical systems theory
  • Statistical inference

Background:

  • Inverse problems are crucial for parameter estimation in dynamical systems.
  • Uncertainty quantification (UQ) is essential for reliable model predictions.
  • Nonlinear systems and various noise types present significant challenges in UQ.

Purpose of the Study:

  • To computationally investigate and compare bootstrapping and asymptotic theory for UQ in nonlinear parameter-dependent dynamical systems.
  • To evaluate the performance of these methods under different data noise conditions (absolute and relative error).
  • To contrast parameter estimates, standard errors, confidence intervals, and computational efficiency.

Main Methods:

  • Development and application of computational frameworks for UQ.
  • Implementation of bootstrapping and asymptotic theory approaches.
  • Analysis of parameter estimation accuracy and uncertainty measures.
  • Comparative assessment of computational performance.

Main Results:

  • Asymptotic theory generally provides more accurate standard errors and narrower confidence intervals compared to bootstrapping.
  • Both methods show varying performance depending on noise characteristics (constant vs. non-constant variance).
  • Asymptotic theory demonstrates superior computational efficiency over bootstrapping.

Conclusions:

  • Asymptotic theory is a computationally efficient and reliable method for UQ in the specified inverse problems.
  • The choice of UQ method should consider the nature of data noise.
  • Further research can explore hybrid approaches or extensions to more complex systems.