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Updated: Jun 8, 2026

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products

Published on: October 4, 2019

Polyketides from Eleutherine bulbosa.

Francesca R Gallo¹, Giovanna Palazzino, Elena Federici

¹Dipartimento del Farmaco, Istituto Superiore di Sanita, I-00161 Rome, Italy. francesca.gallo@iss.it

Natural Product Research

|September 14, 2010

Summary

This summary is machine-generated.

Four new polyketides were isolated from Eleutherine bulbosa bulbs, expanding the known chemical compounds from this plant. These findings contribute to understanding the diverse polyketide structures in Eleutherine bulbosa.

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Area of Science:

Phytochemistry
Natural Product Chemistry

Background:

Eleutherine bulbosa is a plant known to produce various polyketides.
Previous research has identified several compounds from this species.

Purpose of the Study:

To isolate and characterize new polyketide compounds from Eleutherine bulbosa bulbs.
To expand the knowledge of the chemical constituents of Eleutherine bulbosa.

Main Methods:

Isolation of compounds using chemical techniques.
Structure elucidation employing spectroscopic methods.

Main Results:

Four new polyketides were identified: (R)-4-hydroxyeleutherin, eleuthone, eleutherinol-8-O-β-D-glucoside, and isoeleuthoside C.
These new compounds add to the previously isolated list of eleutherin, isoeleutherin, eleutherinol, eleutherol, eleuthoside B, eleuthoside C, hongconin, and elecanacin.
The structures are based on oxydated cyclic systems.

Conclusions:

The study successfully identified novel polyketides from Eleutherine bulbosa.
The findings enhance the understanding of the phytochemical diversity of Eleutherine bulbosa.