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Healthy young and middle age adults: what will it take to vaccinate them for influenza?

Lori Uscher-Pines1, Jurgen Maurer, Arthur Kellerman

  • 1RAND Corporation, 1200 South Hayes Street, Arlington, VA 22202-5050, USA. luscherp@rand.org

Vaccine
|September 15, 2010
PubMed

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Enhance airway patency
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Vaccines are among the most effective tools in preventive medicine, designed to prepare the immune system to recognize and combat infectious agents. By introducing antigens—substances that the immune system identifies as foreign—vaccines stimulate an adaptive immune response that leads to immunological memory. This immunological memory enables the body to mount a faster and more effective response upon future exposures to the actual pathogen.Vaccines can be categorized based on the type of...
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Smallpox

Smallpox is a severe contagious disease caused by the Variola major virus, a double-stranded DNA member of the Poxviridae family.Variola major transmission occurs primarily via inhalation of virus-laden droplets or direct contact with infectious scabs. The incubation period averages approximately seven days, although it may range from 7 to 17 days depending on the inoculum and host factors.Clinically, the prodromal phase is marked by an abrupt onset of high fever, malaise, headache, and myalgia.