Related Experiment Video
Updated: Feb 9, 2026

Development of Organoids from Mouse Pituitary as In Vitro Model to Explore Pituitary Stem Cell Biology
Published on: February 25, 2022
Olfactory ensheathing cells: biology in neural development and regeneration
1Institute of Neuroscience and Key Laboratory of Molecular Neurobiology of Ministry of Education, Neuroscience Research Center of Changzheng Hospital, Second Military Medical University, Shanghai, China.
Abstract:
Olfactory ensheathing cells (OECs) constitute a unique population of glia that accompany and ensheath the primary olfactory axons. They are thought to be critical for spontaneous growth of olfactory axons within the developing and adult olfactory nervous system, and have recently emerged as potential candidates for cell-mediated repair of neural injuries. Here, based on the current research, we give an overview of the biology of OECs in neural development and regeneration. This review starts with a detailed description of the cellular and molecular biological properties of OECs. Their functions in olfactory neurogenesis, olfactory axonal growth and olfactory bulb formation are sequently discussed. We also describe therapeutic applications of OECs for the treatment of a variety of neural lesions, including spinal cord injury, stroke, degenerative diseases, and PNS injuries. Finally, we address issues that may foster a better understanding of OECs in neural development and regeneration.
More Related Videos
07:57Coculture of Axotomized Rat Retinal Ganglion Neurons with Olfactory Ensheathing Glia, as an In Vitro Model of Adult Axonal Regeneration
Published on: November 2, 2020
10:33Transplantation of Olfactory Ensheathing Cells to Evaluate Functional Recovery after Peripheral Nerve Injury
Published on: February 23, 2014
Related Concept Videos
Neural Regulation
Stem Cell Therapy for Tissue Regeneration
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
What is Conservation Biology?
Biological Effects of Radiation
Sustainable Development
Whole Body Regeneration