Protein engineering of chymosin--tailoring the pH profile

Crystallization of Helix pomatia agglutinin (HPA), a protein from the edible snail.

Acta crystallographica. Section D, Biological crystallography·1999

A 2.3 A resolution structure of chymosin complexed with a reduced bond inhibitor shows that the active site beta-hairpin flap is rearranged when compared with the native crystal structure.

Protein engineering·1998

Effect of mutation of lysine-128 of the large subunit of ribulose bisphosphate carboxylase/oxygenase from Anacystis nidulans.

The Biochemical journal·1998

Mutagenesis, biochemical characterization and X-ray structural analysis of point mutants of bovine chymosin.

Protein engineering·1998

Protein engineering loops in aspartic proteinases: site-directed mutagenesis, biochemical characterization and X-ray analysis of chymosin with a replaced loop from rhizopuspepsin.

Protein engineering·1996

Expression and characterisation of chymosin pH optima mutants produced in Trichoderma reesei.

Journal of biotechnology·1993

Fc-engineering for improved cancer immunotherapy.

Biochemical Society transactions·2026

Where metabolism and virulence meet-sulfoxide reductases as determinants of bacterial survival.

Biochemical Society transactions·2026

Molecular mechanisms of Kir channel gating.

Biochemical Society transactions·2026

Communication is key: combinatorial phosphorylation and functional cross-talk in the RNA polymerase II CTD code.

Biochemical Society transactions·2026

The tumor microenvironment in pancreatic cancer: from composition to therapeutic targeting.

Biochemical Society transactions·2026

Deciphering influenza B virus-derived peptides and their presentation by HLA class I molecules.

Biochemical Society transactions·2026

Development of inducible packaging cell line for rAAV production via CRISPR-Cas9 mediated site-specific integration.

Biochemical engineering journal·2026

Nummular Dermatitis Following an Insect Bite in a Patient With Activated Phosphoinositide-3-Kinase Delta Syndrome (APDS): A Case Report and Literature Review.

Cureus·2026

Photocatalytic Golgi Proteomics Reveals Palmitoylation-Regulated Golgiphagy.

Journal of the American Chemical Society·2026

ROS-responsive nanogels enable inhaled CD24 immunotherapy for selective hyperinflammation suppression in severe pneumonia.

Science advances·2026

ZmMYC7 negatively regulates salt tolerance in maize through ZmMAPK3-mediated phosphorylation-dependent proteasomal degradation.

Gene·2026

Optimization of microencapsulation process for the fabrication of methyleugenol microcapsules and investigation of their antifungal effects on Fusarium avenaceum.

Food chemistry·2026

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Protein engineering of chymosin--tailoring the pH profile

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Crystallization of Helix pomatia agglutinin (HPA), a protein from the edible snail.

A 2.3 A resolution structure of chymosin complexed with a reduced bond inhibitor shows that the active site beta-hairpin flap is rearranged when compared with the native crystal structure.

Effect of mutation of lysine-128 of the large subunit of ribulose bisphosphate carboxylase/oxygenase from Anacystis nidulans.

Mutagenesis, biochemical characterization and X-ray structural analysis of point mutants of bovine chymosin.

Protein engineering loops in aspartic proteinases: site-directed mutagenesis, biochemical characterization and X-ray analysis of chymosin with a replaced loop from rhizopuspepsin.

Expression and characterisation of chymosin pH optima mutants produced in Trichoderma reesei.

Fc-engineering for improved cancer immunotherapy.

Where metabolism and virulence meet-sulfoxide reductases as determinants of bacterial survival.

Molecular mechanisms of Kir channel gating.

Communication is key: combinatorial phosphorylation and functional cross-talk in the RNA polymerase II CTD code.

The tumor microenvironment in pancreatic cancer: from composition to therapeutic targeting.

Deciphering influenza B virus-derived peptides and their presentation by HLA class I molecules.

Development of inducible packaging cell line for rAAV production via CRISPR-Cas9 mediated site-specific integration.

Nummular Dermatitis Following an Insect Bite in a Patient With Activated Phosphoinositide-3-Kinase Delta Syndrome (APDS): A Case Report and Literature Review.

Photocatalytic Golgi Proteomics Reveals Palmitoylation-Regulated Golgiphagy.

ROS-responsive nanogels enable inhaled CD24 immunotherapy for selective hyperinflammation suppression in severe pneumonia.

ZmMYC7 negatively regulates salt tolerance in maize through ZmMAPK3-mediated phosphorylation-dependent proteasomal degradation.

Optimization of microencapsulation process for the fabrication of methyleugenol microcapsules and investigation of their antifungal effects on Fusarium avenaceum.

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Protein engineering of chymosin--tailoring the pH profile

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