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Related Experiment Video

Updated: Jun 8, 2026

Microscopic Cyst Resection for the Treatment of Patients Diagnosed with Epididymal Cyst

Microscopic Cyst Resection for the Treatment of Patients Diagnosed with Epididymal Cyst

Published on: March 31, 2023

Foregut duplication cysts in siblings: A case report.

Paul L Davis¹, Kathleen G Gibson, Adele K Evans

¹Medical Center Boulevard, Department of Otolaryngology, 4th Floor Watlington, Winston-Salem, NC 27157, USA. pdavis@wfubmc.edu

International Journal of Pediatric Otorhinolaryngology

|September 15, 2010

Summary

This study reports the first known case of two siblings with foregut duplication cysts in different locations. The findings suggest a possible inherited component for these rare congenital anomalies.

Related Experiment Videos

Last Updated: Jun 8, 2026

Microscopic Cyst Resection for the Treatment of Patients Diagnosed with Epididymal Cyst

Microscopic Cyst Resection for the Treatment of Patients Diagnosed with Epididymal Cyst

Published on: March 31, 2023

Area of Science:

Medical Genetics
Developmental Biology
Pediatric Surgery

Background:

Enteric duplication cysts are rare congenital anomalies originating from foregut-derived epithelium.
These cysts can occur anywhere along the digestive tract, from the head to the abdomen.
Causation remains unclear, with no single embryologic process definitively identified.

Observation:

A case involving two siblings with foregut duplication cysts is presented.
One sibling presented with a cyst in the floor of the mouth.
The other sibling had an esophageal duplication cyst in the thorax.

Findings:

This is the first reported instance of foregut duplication cysts occurring in siblings.
The presentation in distinct anatomical locations (head/neck and thorax) is noteworthy.
The occurrence in close relatives raises questions about potential genetic or inherited factors.

Implications:

This case challenges the understanding of enteric duplication cyst etiology.
It highlights the possibility of an inherited predisposition to foregut duplication cysts.
Further research into the genetic basis of these anomalies is warranted.