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  1. Home
  2. Impact Of New Development Of Ulcer-like Projection On Clinical Outcomes In Patients With Type B Aortic Dissection With Closed And Thrombosed False Lumen.
  1. Home
  2. Impact Of New Development Of Ulcer-like Projection On Clinical Outcomes In Patients With Type B Aortic Dissection With Closed And Thrombosed False Lumen.

Related Experiment Video

Novel and Innovative Hybrid Technique for Type A Aortic Dissection
06:26

Novel and Innovative Hybrid Technique for Type A Aortic Dissection

Published on: March 28, 2025

Impact of new development of ulcer-like projection on clinical outcomes in patients with type B aortic dissection

Takeshi Kitai1, Shuichiro Kaji, Atsushi Yamamuro

  • 1Department of Cardiovascular Medicine, Kobe City Medical Center General Hospital, Chuo-ku, Kobe, Japan.

Circulation
|September 15, 2010

View abstract on PubMed

Summary
This summary is machine-generated.

Related Experiment Videos

Novel and Innovative Hybrid Technique for Type A Aortic Dissection
06:26

Novel and Innovative Hybrid Technique for Type A Aortic Dissection

Published on: March 28, 2025

Newly developing ulcer-like projections (ULP) in patients with type B aortic dissection and closed, thrombosed false lumen are linked to poorer survival and increased adverse events. Careful monitoring is recommended for these patients.

Area of Science:

  • Cardiovascular Medicine
  • Radiology
  • Vascular Surgery

Background:

  • Aortic dissection with closed and thrombosed false lumen (AD with CTFL) is also known as aortic intramural hematoma.
  • Ulcer-like projections (ULP) are a newly identified feature in AD with CTFL.

Purpose of the Study:

  • To investigate the clinical significance of newly developed ulcer-like projections (ULP) in patients diagnosed with type B aortic dissection with closed and thrombosed false lumen (AD with CTFL).

Main Methods:

  • Retrospective analysis of 170 patients with acute type B AD with CTFL treated medically between 1986 and 2008.
  • Assessment of ULP development within 30 days of onset.
  • Correlation of ULP presence and location with survival rates and aorta-related adverse events.

Main Results:

  • 36% of patients developed new ULPs within 30 days.
  • ULP development was significantly associated with poorer survival rates (P=0.037) and increased adverse aorta-related events (P<0.001).
  • ULP in the proximal descending aorta (PD) showed higher event rates (P<0.001); initial aortic diameter and ULP in PD were strong predictors of adverse events.

Conclusions:

  • Initial aortic diameter and ULP development in the proximal descending aorta are significant predictors of adverse outcomes in type B AD with CTFL.
  • Patients with newly developed ULPs require closer surveillance imaging due to increased risk.