[Diagnosis of recent posterolateral myocardial infarction: an electrocardiographic, echocardiographic and
G P Perna1, G Valle, M P Salvatori
1Servizio di Cardiologia e UTIC, Ospedale Regionale Generale Casa Sollievo della Sofferenza S. Giovanni Rotondo Foggia.
Insights
Electrocardiography (ECG) is more sensitive than 2D echocardiography for detecting previous posterolateral myocardial infarction, especially when combined with specific criteria. Echocardiography may miss these events if inferior infarction is also present.
Area of Science:
- Cardiology
- Medical Imaging
- Diagnostic Tools
Background:
- Previous myocardial infarction (MI) can lead to specific regional wall motion abnormalities.
- Posterolateral MI poses diagnostic challenges, often requiring advanced imaging techniques.
- Assessing the diagnostic accuracy of non-invasive methods for MI detection is crucial.
Purpose of the Study:
- To evaluate the sensitivity and specificity of standard electrocardiography (ECG) and 2D echocardiography in recognizing previous posterolateral myocardial infarction.
- To compare the diagnostic performance of ECG and 2D echocardiography in patients with isolated posterolateral defects versus those with combined posterolateral and inferoapical defects.
Main Methods:
- Studied 64 patients with previous MI and confirmed posterolateral defects via 201TI scintigraphy, divided into isolated posterolateral (n=47) and combined defects (n=17).
- Included 30 healthy controls.
- Calculated sensitivity, specificity, and predictive values for ECG criteria and 2D echocardiography (wall motion abnormalities).
- Utilized multivariate analysis for ECG data.
Main Results:
- A positive T wave in V1 on ECG showed 100% sensitivity and 76% specificity for posterolateral MI.
- A 2-variable ECG model (positive T wave in V1 + R/S ratio ≥ 1 in V1-V2) achieved 95-100% sensitivity and 80% specificity.
- 2D echocardiography demonstrated 70% sensitivity for isolated posterolateral MI but only 29% sensitivity when inferior MI was also present, with 100% specificity.
- ECG proved more sensitive but less specific than 2D echocardiography.
Conclusions:
- Standard ECG is a highly sensitive tool for identifying previous posterolateral myocardial infarction.
- 2D echocardiography's sensitivity for posterolateral MI is significantly reduced in the presence of associated inferior MI.
- Multivariate ECG analysis offers improved diagnostic accuracy for detecting posterolateral myocardial infarction.
Abstract:
ECG and 2D echocardiography were studied in 64 patients with previous myocardial infarction and evidence of posterolateral fixed defect at 201 TI scintigraphy. The defect was isolated posterolateral in 47 patients (group 1), and posterolateral + inferoapical in 17 (group 2). Thirty subjects with no history of myocardial infarction and no 201 TI defects constituted the control group. We calculated sensitivity, specificity and predictive value of ECG and 2D echocardiography (pertinent wall motion abnormality) in the recognition of posterolateral infarction. ECG data were also analyzed using multivariate analysis. Among the ECG criteria, a positive T wave in V1 proved to be 100% sensitive and 76% specific both in group 1 and in group 2. At multivariate analysis, a 2-variable model (positive T wave inV1 + R/S ratio greater than or equal to 1 in V1-V2) had a sensitivity of 95 and 100% in group 1 and 2, respectively; the specificity was 80%. A 3-variable model (+ R wave duration in V1-V2 greater than or equal to 0.04 sec) proved to be less sensitive (70 and 88% in group 1 and 2, respectively), with a specificity of 97%. A pertinent dyssynergy at 2D echocardiography was 70% sensitive for posterolateral myocardial infarction in group 1, but only 29% in group 2, with a specificity of 100%. These results indicate: 1) standard ECG is more sensitive but less specific than 2D echocardiography in the recognition of previous postolateral myocardial infarction; 2) the recognition of posterolateral involvement can be frequently missed by 2D echocardiography in patients with associated inferior myocardial infarction.
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