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Updated: Jun 8, 2026

Single-molecule Super-resolution Imaging of Phosphatidylinositol 4,5-bisphosphate in the Plasma Membrane with Novel Fluorescent Probes
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Single-molecule Super-resolution Imaging of Phosphatidylinositol 4,5-bisphosphate in the Plasma Membrane with Novel Fluorescent Probes

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Visualization of PKA activity in plasma membrane microdomains

Charlene Depry1, Michael D Allen, Jin Zhang

  • 1Department of Pharmacology and Molecular Sciences, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

Molecular Biosystems
|September 15, 2010
PubMed
Summary

Membrane rafts negatively regulate β-adrenergic receptor (β-AR) stimulated Protein Kinase A (PKA) activity. Rafts exhibit higher basal PKA activity, highlighting their role in PKA signaling dynamics within plasma membrane microdomains.

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