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Selective α-defluorination of polyfluorinated esters and amides using SmI2/Et3N/H2O

Jenny Wettergren1, Tobias Ankner, Göran Hilmersson

  • 1Department of Chemistry, University of Gothenburg, Kemivägen 10, SE-412 96 Göteborg, Sweden.

Chemical Communications (Cambridge, England)
|September 15, 2010
PubMed

Abstract:

SmI(2)/H(2)O promotes selective α-monodefluorinations, while addition of an amine results in complete α-defluorination reactions.

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