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Site-Directed Immobilization of Bone Morphogenetic Protein 2 to Solid Surfaces by Click Chemistry
Published on: March 29, 2018
[Percutaneous administration of recombinant human bone morphogenetic protein-7 (rhBMP-7) after callus distraction.
1Abt. für Orthopädie und Unfallchirurgie, Berufsgenossenschaftliche Unfallklinik Murnau e.V., Prof.-Küntscher-Str. 8, 82418, Murnau, Deutschland. florian.hoegel@bgu-murnau.de
Der Unfallchirurg
|September 15, 2010
Abstract:
Two cases of increased bone density after callus distraction are described following percutaneous administration of 3.5 mg recombinant bone morphogenetic protein-7 (rhBMP-7). Both patients underwent segmental resection and segmental transport for osteomyelitis of the long bones (femur and tibia) but no callus maturation occurred. After percutaneous administration of rhBMP-7 the callus density increased in both cases.

