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[Drug therapy of glaucoma]
1Universitäts-Augenklinik, Köln, Bundesrepublik Deutschland.
Fortschritte Der Ophthalmologie : Zeitschrift Der Deutschen Ophthalmologischen Gesellschaft
|January 1, 1990
Summary
This review updates medical therapy for open-angle glaucoma, discussing outdated and current treatments. Future treatments include new drug designs and topical carbonic anhydrase inhibitors for better intraocular pressure control.
Area of Science:
- Ophthalmology
- Pharmacology
Context:
- Open-angle glaucoma management requires continuous therapeutic advancements.
- Traditional medical therapies are evolving with new drug delivery systems and agents.
Purpose:
- To provide an updated overview of medical therapies for open-angle glaucoma.
- To discuss current and future pharmacological strategies for glaucoma management.
Summary:
- The review critically examines current antiglaucoma medications, deeming irreversible cholinesterase inhibitors, high-dose clonidine, and epinephrine preparations outdated.
- It highlights promising future treatments such as pro-drugs, improved pharmaceutical preparations, topical carbonic anhydrase inhibitors, apraclonidine, and prostaglandin derivatives.
- Experimental agents are also presented, offering a glimpse into the evolving armamentarium against glaucoma.
Impact:
- Informs clinicians about the current landscape and future directions in glaucoma pharmacotherapy.
- Guides pharmaceutical research and development towards more effective and targeted glaucoma treatments.