Related Experiment Video
Updated: Jun 8, 2026

Quantification of Metal Leaching in Immobilized Metal Affinity Chromatography
Published on: January 17, 2020
Metal-metal reactivity: Houston, we have a problem!
Thomas P Schmalzried1, John V Tiberi
1Joint Replacement Institute at St Vincent Medical Center, Los Angeles, California, USA. schmalzried@earthlink.net
Symptomatic pseudotumor in hip arthroplasty is linked to increased combined anteversion, not female sex or component size. Proper component positioning, including lateral opening and version angles, is crucial for preventing this complication.
Area of Science:
- Orthopedic Surgery
- Biomechanical Engineering
Background:
- Symptomatic pseudotumor is a rare but serious complication following hip arthroplasty.
- Previous studies have suggested associations with patient sex and implant size, but the underlying biomechanics remain unclear.
Purpose of the Study:
- To investigate the biomechanical factors, specifically component positioning, associated with the development of symptomatic pseudotumor after hip arthroplasty.
- To identify optimal parameters for acetabular and femoral component placement to minimize pseudotumor risk.
Main Methods:
- Retrospective analysis of hip arthroplasty cases requiring revision for symptomatic pseudotumor.
- Comparison of acetabular component lateral opening angle, acetabular anteversion, and femoral version between pseudotumor cases and controls.
- Analysis of patient demographics and native hip anatomy, including congenital dysplasia.
Main Results:
- Three hips (0.51% incidence) required revision for pseudotumor, all with 50-mm acetabular components and increased acetabular anteversion (mean 27.1° vs 16.4°).
- Increased combined anteversion was identified as a common mechanical factor in pseudotumor formation.
- Congenital dysplasia, characterized by shallow sockets and high anteversion, may predispose to adverse joint mechanics.
Conclusions:
- Increased combined anteversion, rather than female sex or small component size, is the primary mechanical factor leading to pseudotumor.
- Accurate assessment of acetabular lateral opening angle (<50°), acetabular anteversion, and femoral version is essential for satisfactory component positioning.
- Adjusting acetabular lateral opening angle in dysplastic cases with altered neck-shaft angles is necessary to ensure proper head capture and bearing function.
More Related Videos
12:18Co-localizing Kelvin Probe Force Microscopy with Other Microscopies and Spectroscopies: Selected Applications in Corrosion Characterization of Alloys
Published on: June 27, 2022
04:53Electric Cell-Substrate Sensing for Real-Time Evaluation of Metal-Organic Framework Toxicological Profiles
Published on: May 26, 2023
Related Concept Videos
Properties of Organometallic Compounds
Metal-Ligand Bonds
In these complexes, transition metals form coordinate covalent bonds, a kind of Lewis acid-base interaction in which both of the electrons in the bond are contributed by a donor (Lewis base) to an electron acceptor (Lewis acid). The Lewis acid in...
Bonding in Metals
Complexation Equilibria: Factors Influencing Stability of Complexes
Metallic Solids
All metallic solids exhibit high thermal and electrical conductivity, metallic luster, and malleability. Many...
Properties of Transition Metals