Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Magnetic Resonance Imaging

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

Imaging Studies I: CT and MRI

Imaging Studies I: CT and MRI

Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Photon-counting CT: image quality evaluation in patients with tibial plateau fracture treated with metallic osteosynthesis material.

European radiology experimental·2026

Same author

Evaluating osseointegration, bone remodeling and osteolysis after total wrist arthroplasty using photon-counting detector CT.

Skeletal radiology·2026

Same author

Improved coronary CT angiography image quality using photon-counting detector CT in SCAPIS reexamination: scan protocol and comparative analysis.

European journal of radiology·2026

Same author

Swedish national recommendations for MR safety 2026.

Insights into imaging·2026

Same author

Detection of hepatic steatosis with ultrasound-guided attenuation parameter (UGAP) in metabolic dysfunction-associated steatotic liver disease (MASLD) compared with proton density fat fraction (PDFF): Impact of measurement number and region of interest (ROI) location.

Ultrasound (Leeds, England)·2026

Same author

Diagnostic accuracy of energy-integrating and standard-resolution photon counting detector CT for coronary artery stenosis grading in CCTA: A comparative study.

Journal of cardiovascular computed tomography·2026

Search research articles

Related Experiment Video

Updated: Jun 8, 2026

High-resolution Structural Magnetic Resonance Imaging of the Human Subcortex In Vivo and Postmortem

High-resolution Structural Magnetic Resonance Imaging of the Human Subcortex In Vivo and Postmortem

Published on: December 30, 2015

Quantitative MRI in isotropic spatial resolution for forensic soft tissue documentation. Why and how?

Christian Jackowski¹, Marcel J B Warntjes, Johan Kihlberg

¹Center for Medical Image Science and Visualization (CMIV), University Hospital, University of Linköping, SE-58185 Linköping, Sweden. christian.jackowski@irm.uzh.ch

Journal of Forensic Sciences

|September 16, 2010

Summary

Isotropic and quantified postmortem MRI (IQpmMR) provides detailed 3D tissue characterization by mapping T1, T2, and PD values. This enables advanced visualization and potential computer-aided diagnosis for postmortem analysis.

More Related Videos

Assessing Cortical Cerebral Microinfarcts on High Resolution MR Images

Assessing Cortical Cerebral Microinfarcts on High Resolution MR Images

Published on: November 20, 2015

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease

Published on: December 18, 2016

Related Experiment Videos

Last Updated: Jun 8, 2026

High-resolution Structural Magnetic Resonance Imaging of the Human Subcortex In Vivo and Postmortem

High-resolution Structural Magnetic Resonance Imaging of the Human Subcortex In Vivo and Postmortem

Published on: December 30, 2015

Assessing Cortical Cerebral Microinfarcts on High Resolution MR Images

Assessing Cortical Cerebral Microinfarcts on High Resolution MR Images

Published on: November 20, 2015

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease

Published on: December 18, 2016

Area of Science:

Medical Imaging
Forensic Science
Biophysics

Background:

Postmortem imaging requires advanced techniques for detailed tissue analysis.
Current methods may lack sufficient soft tissue discrimination for comprehensive evaluation.

Purpose of the Study:

To introduce and evaluate Isotropic and Quantified Postmortem Magnetic Resonance (IQpmMR) for high-resolution T1, T2, and PD quantification.
To demonstrate the utility of IQpmMR for 3D tissue characterization and visualization in postmortem specimens.

Main Methods:

Performed high isotropic resolution quantification of T1, T2, and PD relaxation times on postmortem specimens.
Utilized a T1-T2-PD space to cluster similar tissue voxels.
Implemented volume rendering software for 3D color-encoded visualization of tissues and pathologies.

Main Results:

IQpmMR enabled sophisticated 3D postprocessing, including reformatting and volume rendering.
Tissue characterization was achieved by combining T1, T2, and PD values, forming distinct clusters in the T1-T2-PD space.
Color encoding of tissues and pathologies in 3D models demonstrated superior soft tissue discrimination compared to CT.

Conclusions:

IQpmMR offers powerful soft tissue discrimination and advanced 3D visualization capabilities for postmortem analysis.
The technique allows for calculation of any image plane contrast and 3D color-encoded volume rendering.
IQpmMR data can support future computer-aided diagnosis, such as hemorrhage distribution analysis based on tissue-specific T1-T2-PD vectors.