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Cysticercal meningoencephalitis.

S Venkataraman1, A K Roy, R M Dhamija

  • 1Neurological Centre, Army Hospital, Delhi Cantt.

The Journal of the Association of Physicians of India
|October 1, 1990
PubMed
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Neurocysticercosis (NCC) can manifest as meningoencephalitis, a serious brain inflammation. This study highlights NCC as a treatable cause of meningoencephalitis, with most patients showing improvement after therapy.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Parasitology

Background:

  • Meningoencephalitis presents with diverse etiologies.
  • Neurocysticercosis (NCC) is a significant parasitic infection of the central nervous system.

Purpose of the Study:

  • To investigate the clinical presentation and diagnostic features of neurocysticercosis (NCC) presenting as meningoencephalitis.
  • To assess the outcomes of NCC-induced meningoencephalitis.

Main Methods:

  • Retrospective analysis of 170 neurocysticercosis cases over 13 years.
  • Diagnosis confirmed via subcutaneous nodule histopathology, CT scans, and autopsy.
  • Clinical data including symptoms, neurological signs, and cerebrospinal fluid analysis were reviewed.

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Main Results:

  • 15 out of 170 (8.8%) neurocysticercosis cases presented with meningoencephalitis.
  • Common symptoms included fever (12), seizures (10), and altered sensorium (7).
  • Papilledema was present in all cases; cerebrospinal fluid abnormalities were noted in 8/13.

Conclusions:

  • Neurocysticercosis is an important, often treatable, cause of meningoencephalitis.
  • Early diagnosis and appropriate therapy can lead to favorable outcomes in most patients.
  • NCC should be considered in the differential diagnosis of meningoencephalitis, especially in endemic areas.