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Related Concept Videos

One-Compartment Model: IV Infusion01:09

One-Compartment Model: IV Infusion

Intravenous (IV) infusion is often utilized when continuous and controlled drug delivery is necessary, such as during surgery or in the treatment of chronic diseases. This method offers numerous advantages, including immediate drug action, precise control over dosage, and bypassing the first-pass metabolism.
The one-compartment model for IV infusion uses mathematical equations to describe the rate of change in drug quantity in the body. At steady-state or infusion equilibrium, the drug input...
IV Infusion to Oral Dosing: Conversion Methods01:28

IV Infusion to Oral Dosing: Conversion Methods

The development of extended-release formulations has facilitated the transition from intravenous to oral medication, offering a more convenient and patient-friendly approach to drug administration. This transition, however, requires careful management to ensure that therapeutic drug levels are maintained, preserving efficacy and avoiding adverse effects. Understanding pharmacokinetic principles and dosage calculations is critical during this process.Pharmacokinetics of the...
Two-Compartment Open Model: IV Infusion01:15

Two-Compartment Open Model: IV Infusion

A two-compartment model is a vital tool in pharmacokinetics, providing an essential understanding of drug behavior, especially for those administered via zero-order intravenous infusion. This model outlines two compartments: the central compartment, where elimination occurs, and the peripheral compartment.
The model illustrates the decrease in plasma drug concentration from the central compartment with a specific equation. It shows that under steady-state conditions, the drug's input rate...
Drug Accumulation During Multiple Dosing: Intermittent IV Infusions01:24

Drug Accumulation During Multiple Dosing: Intermittent IV Infusions

Intermittent intravenous (IV) infusion is a method of drug administration where medications are delivered over short infusion periods followed by intervals of no drug delivery. This approach helps to prevent sustained high drug concentrations in the bloodstream, reducing the risk of adverse effects associated with prolonged exposure. Unlike continuous infusion, steady-state concentrations may not be achieved during a single dosing cycle but can be reached through repeated...
Parenteral Drug Delivery Systems: Injectables, Implants, and Infusion Devices01:28

Parenteral Drug Delivery Systems: Injectables, Implants, and Infusion Devices

Parenteral drug delivery systems play a crucial role in modern therapeutics by enabling the direct administration of drugs into the systemic circulation, bypassing the gastrointestinal tract. These systems are particularly valuable for poorly absorbed oral medications that are unstable in the digestive environment or require rapid onset or sustained therapeutic levels. Delivery is achieved through intravenous, intramuscular, or subcutaneous routes, each selected based on the drug's properties...
Nursing Clinical Information System01:27

Nursing Clinical Information System

Nursing Clinical Information System (NCIS)
A Nursing Clinical Information System (NCIS) is a specialized type of healthcare information system tailored to meet the unique needs of nursing practice. It incorporates the principles of nursing informatics to streamline information management and improve the quality of care delivery.
Critical attributes of NCIS include:

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Related Experiment Video

Updated: Jun 8, 2026

A Protocol to Set Up Needle-Free Connector with Positive Displacement on Central Venous Catheter in Intensive Care Unit
09:57

A Protocol to Set Up Needle-Free Connector with Positive Displacement on Central Venous Catheter in Intensive Care Unit

Published on: July 13, 2019

Development of an infusion alliance.

Lynn Hadaway1

  • 1Lynn Hadaway Associates, Inc., Milner, GA 30257, USA. lynn@hadawayassociates.com

Journal of Infusion Nursing : the Official Publication of the Infusion Nurses Society
|September 16, 2010
PubMed
Summary

Infusion therapy requires better knowledge management to ensure patient safety, as errors and complications persist. Reinstating infusion therapy teams is crucial for modern healthcare organizations.

Area of Science:

  • Healthcare Management
  • Patient Safety
  • Clinical Practice

Background:

  • Infusion therapy is a complex and pervasive healthcare intervention.
  • Current healthcare systems lack sufficient investment in knowledge management and human capital for infusion therapy.
  • Catheter complications, medication errors, and transfusion errors highlight patient safety issues.

Purpose of the Study:

  • To underscore the critical need for enhanced organizational knowledge management in infusion therapy.
  • To advocate for the reinstatement and recognition of specialized infusion therapy teams.
  • To highlight the role of infusion alliances in improving patient safety and care quality.

Main Methods:

  • Analysis of current trends in healthcare delivery and patient safety incidents related to infusion therapy.

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A Model of Chronic Nutrient Infusion in the Rat
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A Model of Chronic Nutrient Infusion in the Rat

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Construction and Implantation of a Microinfusion System for Sustained Delivery of Neuroactive Agents.
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Construction and Implantation of a Microinfusion System for Sustained Delivery of Neuroactive Agents.

Published on: March 17, 2008

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Last Updated: Jun 8, 2026

A Protocol to Set Up Needle-Free Connector with Positive Displacement on Central Venous Catheter in Intensive Care Unit
09:57

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Published on: July 13, 2019

A Model of Chronic Nutrient Infusion in the Rat
08:18

A Model of Chronic Nutrient Infusion in the Rat

Published on: August 14, 2013

Construction and Implantation of a Microinfusion System for Sustained Delivery of Neuroactive Agents.
12:17

Construction and Implantation of a Microinfusion System for Sustained Delivery of Neuroactive Agents.

Published on: March 17, 2008

  • Review of the impact of reduced infusion therapy teams on patient outcomes.
  • Examination of the cost-cutting strategies affecting specialized healthcare teams.
  • Main Results:

    • Significant patient safety risks exist due to inadequate knowledge management in infusion therapy.
    • Decreased numbers of infusion therapy teams correlate with increased complications.
    • Infusion therapy teams are essential for mitigating risks and ensuring optimal patient care.

    Conclusions:

    • Investment in knowledge management and specialized infusion therapy teams is vital for patient safety.
    • The concept of an "infusion alliance" offers a framework for integrated and safe infusion practices.
    • Modern healthcare organizations must prioritize and integrate infusion therapy expertise for effective patient care.