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Updated: Jun 8, 2026

Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint
Published on: July 22, 2021
[Guidelines for the management of knee and hip osteoarthritis: For whom? Why? To do what?]
Yves Henrotin1, Xavier Chevalier
1Université de Liège, CHU Sart-Tilman, institut de pathologie, unité de recherche sur l'os et cartilage (UROC), +5, 4000 Liège, Belgique. yhenrotin@ulg.ac.be
Abstract:
This paper summarizes the guidelines published by the Osteoarthritis research society International (OARSI) and compares these guidelines with others. The OARSI guidelines are based on a systematic review of the literature, a meta-analysis and an expert consensus. The OARSI has developed 25 guidelines including 8 for pharmacology modalities, 12 for non-pharmacology modalities and 5 for surgery modalities. The usefulness of the guidelines in the daily practice is very low. The barriers for the guidelines implementation are the lack of interest of the practitioners, the lack of scientific advances in the OA diagnosis and treatments and the low applicability of these guidelines in the daily practice.
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