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Updated: Jun 8, 2026

A Real-time Potency Assay for Chimeric Antigen Receptor T Cells Targeting Solid and Hematological Cancer Cells

A Real-time Potency Assay for Chimeric Antigen Receptor T Cells Targeting Solid and Hematological Cancer Cells

Published on: November 12, 2019

Capability and clinical success.

Robert L Ferrer¹, Alejandra Varela Carrasco

¹Department of Family and Community Medicine, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229-3900, USA. FerrerR@uthscsa.edu

Annals of Family Medicine

|September 17, 2010

Summary

This summary is machine-generated.

Improving chronic disease management requires addressing social determinants of health. The capability framework offers a novel approach by focusing on real opportunities for healthy lifestyles, integrating personal and environmental factors.

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Last Updated: Jun 8, 2026

A Real-time Potency Assay for Chimeric Antigen Receptor T Cells Targeting Solid and Hematological Cancer Cells

A Real-time Potency Assay for Chimeric Antigen Receptor T Cells Targeting Solid and Hematological Cancer Cells

Published on: November 12, 2019

Area of Science:

Public Health
Health Behavior
Social Determinants of Health

Background:

Chronic disease outcomes are often poor due to factors beyond healthcare control, such as patient self-management.
Social and environmental factors significantly influence patients' ability to manage their health behaviors and chronic conditions.
Current clinical approaches inadequately address these environmental determinants of health.

Observation:

Patient self-management of chronic diseases is heavily influenced by social and environmental constraints.
The healthcare system's response to environmental determinants of health is underdeveloped.
The capability framework offers a potential strategy for addressing social determinants in clinical practice and community initiatives.

Findings:

The capability framework defines capability as the real opportunity to achieve a desired lifestyle.
This framework emphasizes material conditions that limit real opportunities.
It highlights the interplay between personal resources and the social environment in shaping health opportunities.

Implications:

The capability framework can guide clinical practice in addressing social determinants of health.
It provides a structure for planning and evaluating community-based interventions for chronic diseases.
Applying this framework can improve patient outcomes by enhancing real opportunities for healthy living and behavior change.