Understanding the structure and function of the immunological synapse
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Updated: Jun 8, 2026

Imaging the Human Immunological Synapse
Published on: December 26, 2019
Michael L Dustin1, Arup K Chakraborty, Andrey S Shaw
1Program in Molecular Pathogenesis, Skirball Institute of Biomolecular Medicine and Department of Pathology, New York University, New York, New York 10016, USA.
Abstract:
The immunological synapse has been an area of very active scientific interest over the last decade. Surprisingly, much about the synapse remains unknown or is controversial. Here we review some of these current issues in the field: how the synapse is defined, its potential role in T-cell function, and our current understanding about how the synapse is formed.
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