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Updated: Jun 8, 2026

Millifluidics for Chemical Synthesis and Time-resolved Mechanistic Studies

Millifluidics for Chemical Synthesis and Time-resolved Mechanistic Studies

Published on: November 27, 2013

Continuous flow synthesis of nanoparticles using ceramic microfluidic devices.

S Gómez-de Pedro¹, M Puyol, J Alonso-Chamarro

¹Departament de Química, Facultat de Ciències, Edifici Cn, Universitat Autònoma de Barcelona, Bellaterra, Spain.

|September 17, 2010

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This study introduces a low-temperature co-fired ceramics (LTCC) microfluidic system for gold nanoparticle synthesis. This cost-effective, rapid method advances lab-scale production to pilot-line processes.

Area of Science:

Materials Science
Nanotechnology
Chemical Engineering

Background:

Microfluidic systems offer precise control for chemical synthesis.
Traditional microfluidic fabrication can be costly and time-consuming.
Gold nanoparticles have diverse applications in catalysis, sensing, and medicine.

Purpose of the Study:

To develop a cost-effective and rapid microfluidic system for gold nanoparticle synthesis and functionalization.
To leverage low-temperature co-fired ceramics (LTCC) technology for microfluidic device fabrication.
To demonstrate the scalability of the developed system from laboratory to pilot-line production.

Main Methods:

Fabrication of a microfluidic system using low-temperature co-fired ceramics (LTCC) technology.

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Last Updated: Jun 8, 2026

Millifluidics for Chemical Synthesis and Time-resolved Mechanistic Studies

Millifluidics for Chemical Synthesis and Time-resolved Mechanistic Studies

Published on: November 27, 2013

A Modular Microfluidic Technology for Systematic Studies of Colloidal Semiconductor Nanocrystals

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One-phase synthesis and functionalization of monodispersed gold nanoparticles within the microfluidic system.

Utilizing the advantages of ceramic materials, including versatility and chemical resistivity.

Main Results:

Successful reproducible synthesis and functionalization of monodispersed gold nanoparticles.
Demonstration of fast prototyping capabilities of LTCC technology for microfluidic systems.
Significant reduction in cost and production time compared to conventional methods.

Conclusions:

The LTCC-based microfluidic system provides a rapid, low-cost, and automated approach for gold nanoparticle synthesis.
The system's design allows for integration of multiple components, enhancing its versatility.
This technology is well-suited for scaling up gold nanoparticle production from laboratory to pilot-line processes.