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Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

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Characteristics of optic disc melanocytomas presenting with visual dysfunction.

Saba Al-Rashaed¹, Emad B Abboud, Sawsan R Nowilaty

¹Vitreoretinal Division, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.

Middle East African Journal of Ophthalmology

|September 17, 2010

Summary

Optic disc melanocytomas can cause visual impairment through various mechanisms, despite their typically benign nature. This study details five cases of vision loss linked to these optic nerve head tumors.

Keywords:

Melanocytoma Optic Disc Visual Function

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Area of Science:

Ophthalmology
Oncology
Medical Imaging

Background:

Melanocytomas of the optic disc are rare tumors.
While often benign, they can lead to visual disturbances.

Purpose of the Study:

To describe five cases of optic disc melanocytoma.
To illustrate tumor-related visual impairment caused by these lesions.

Main Methods:

Retrospective review of five patients with optic disc melanocytoma.
Analysis of demographic and clinical data, including visual acuity, visual fields, and imaging (fundus photography, fluorescein angiography, ultrasound).

Main Results:

Visual dysfunction was observed in all five cases.
Specific findings included macular edema, optic atrophy, choroidal neovascularization, optic disc swelling, and visual field defects.

Conclusions:

Optic disc melanocytomas, despite a generally benign course, can impair vision.
Multiple mechanisms contribute to visual dysfunction in these tumors.