Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

An intelligent point-of-care photoacoustic and ultrasound dual-modality imaging system for Rheumatoid arthritis in fingers: Technical development and initial clinical test.

Photoacoustics·2026
Same author

Imprinted high-<i>Q</i> polymer micro-ring resonator array for high-resolution photoacoustic tomography.

Opto-electronic advances·2026
Same author

Gas vesicle-expressing human pluripotent stem cells enable multimodal ultrasound and optical coherence tomographic imaging.

BMC biotechnology·2026
Same author

Fiber-Tip Surface-Micromachined Optical Ultrasound Transducer (SMOUT) Probe for Acoustic Detection Induced by Ultrahigh Dose Rate (UHDR) Electron Beam.

IEEE sensors journal·2026
Same author

Ionizing radiation acoustic beam localization: one step towards "proton surgery".

medRxiv : the preprint server for health sciences·2026
Same author

Genetic Variations in the M6A Modification Pathway as Potential Predictors of Imatinib Secondary Resistance in Gastrointestinal Stromal Tumors.

Journal of clinical medicine·2026

Related Experiment Video

Updated: Jun 8, 2026

In Vivo Optical Imaging of Brain Tumors and Arthritis Using Fluorescent SapC-DOPS Nanovesicles
09:04

In Vivo Optical Imaging of Brain Tumors and Arthritis Using Fluorescent SapC-DOPS Nanovesicles

Published on: May 2, 2014

Optical imaging: new tools for arthritis.

David Chamberland1, Yebin Jiang, Xueding Wang

  • 1Department of Radiology, University of Michigan School of Medicine, Ann Arbor, 48109, USA.

Integrative Biology : Quantitative Biosciences From Nano to Macro
|September 17, 2010
PubMed
Summary
This summary is machine-generated.

Optical imaging offers a promising, non-invasive approach for early arthritis diagnosis and monitoring. This advanced technique overcomes limitations of conventional methods, aiding in evaluating disease progression and treatment response.

More Related Videos

Automated Joint Space Detection Improves Bone Segmentation Accuracy
06:45

Automated Joint Space Detection Improves Bone Segmentation Accuracy

Published on: November 28, 2025

Non-invasive In Vivo Fluorescence Optical Imaging of Inflammatory MMP Activity Using an Activatable Fluorescent Imaging Agent
06:46

Non-invasive In Vivo Fluorescence Optical Imaging of Inflammatory MMP Activity Using an Activatable Fluorescent Imaging Agent

Published on: May 8, 2017

Related Experiment Videos

Last Updated: Jun 8, 2026

In Vivo Optical Imaging of Brain Tumors and Arthritis Using Fluorescent SapC-DOPS Nanovesicles
09:04

In Vivo Optical Imaging of Brain Tumors and Arthritis Using Fluorescent SapC-DOPS Nanovesicles

Published on: May 2, 2014

Automated Joint Space Detection Improves Bone Segmentation Accuracy
06:45

Automated Joint Space Detection Improves Bone Segmentation Accuracy

Published on: November 28, 2025

Non-invasive In Vivo Fluorescence Optical Imaging of Inflammatory MMP Activity Using an Activatable Fluorescent Imaging Agent
06:46

Non-invasive In Vivo Fluorescence Optical Imaging of Inflammatory MMP Activity Using an Activatable Fluorescent Imaging Agent

Published on: May 8, 2017

Area of Science:

  • Biomedical Imaging
  • Medical Diagnostics
  • Optical Physics

Background:

  • Arthritis is a prevalent condition causing significant disability, necessitating effective diagnostic and monitoring tools.
  • Current imaging modalities (radiography, CT, MRI, ultrasound, nuclear imaging) have limitations including radiation, poor contrast, high cost, and long scan times.
  • There is a need for advanced imaging techniques that are non-ionizing, non-invasive, and offer high sensitivity for arthritis evaluation.

Purpose of the Study:

  • To explore the potential of nonionizing noninvasive optical imaging for arthritis.
  • To highlight optical imaging's advantages over conventional methods for early diagnosis and disease monitoring.
  • To review various optical techniques applicable to arthritis assessment.

Main Methods:

  • Review of advancements in optical imaging modalities for arthritis.
  • Discussion of techniques including fluorescence imaging, diffuse optical tomography, Fourier transform infrared spectroscopy, and photoacoustic tomography.
  • Focus on optical detection of molecular and hemodynamic changes in arthritic joints.

Main Results:

  • Optical imaging, particularly fluorescence imaging, shows high sensitivity for contrast agent detection, aiding early diagnosis.
  • Optical techniques can differentiate early inflammatory changes in synovial fluid.
  • Diffuse optical tomography and photoacoustic tomography can visualize hemodynamic changes like angiogenesis and hypoxia.

Conclusions:

  • Optical imaging provides sensitive, non-invasive methods for early arthritis detection and monitoring.
  • These techniques offer advantages over conventional imaging by avoiding ionizing radiation and providing better tissue contrast.
  • Optical methods can quantify hemodynamic properties, crucial for understanding early-stage inflammatory arthritis.