Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Nephrotic Syndrome I : Introduction01:24

Nephrotic Syndrome I : Introduction

Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of fluid...
Nephrons01:10

Nephrons

The kidneys are intricate organs with millions of working units known as nephrons. Each nephron features two major structures: the renal corpuscle, which facilitates blood plasma filtration, and the renal tubule, which handles the glomerular filtrate. Blood supply is directly linked to the nephrons. The renal corpuscle consists of the glomerulus, a capillary network, and the Bowman's capsule, a double-walled epithelial structure that encases the glomerulus. The filtering of blood plasma happens...
Nephrotic Syndrome III : Nursing Management01:24

Nephrotic Syndrome III : Nursing Management

Nursing management for nephrotic syndrome adapts as the disease progresses, with strategies evolving to address advancing symptoms and complications.Early-Stage Management In the early stages, nursing interventions for nephrotic syndrome resemble those used in managing acute glomerulonephritis, focusing on symptom monitoring, fluid balance, and managing mild to moderate edema.Vital Signs: Regularly monitor blood pressure, pulse, respiratory rate, and temperature to promptly identify...
Nephrotic Syndrome II : Assessment and Medical Management01:26

Nephrotic Syndrome II : Assessment and Medical Management

IntroductionNephrotic syndrome is a kidney disorder marked by excessive protein loss in the urine, leading to various systemic complications. This condition often results from damage to the glomeruli—the kidney's filtering units—causing proteinuria, low blood protein levels, and fluid retention. Understanding the assessment, diagnosis, and management of nephrotic syndrome is essential for effective treatment and prevention of further kidney damage.AssessmentPatient History: Document any history...
Diabetic Nephropathy01:28

Diabetic Nephropathy

Definition Diabetic nephropathy is a chronic kidney complication that results from prolonged hyperglycemia.Prevalence It is the most common cause of chronic kidney disease (CKD) and end-stage renal disease (ESRD) worldwide, affecting up to half of individuals with diabetes.Pathophysiology • Sustained hyperglycemia triggers multiple hemodynamic and metabolic changes in the kidney. • Early in the disease, increased renal blood flow and glomerular hyperfiltration occur due to afferent arteriolar...
Acute Kidney Injury II: Pathophysiology01:29

Acute Kidney Injury II: Pathophysiology

Acute kidney injury (AKI) causes are categorized into three primary categories based on the location of the injury: prerenal, intrarenal (or intrinsic), and postrenal causes. This classification guides clinical management and illustrates how different pathways can impair kidney function.Etiology and Pathophysiology of Acute Kidney Injury1. Prerenal causesEtiology: Prerenal Acute Kidney Injury, the most common type, occurs when reduced blood flow to the kidneys decreases filtration capacity...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A large annular plaque on the right forearm slowly extending into a graft site.

Clinical and experimental dermatology·2021
Same author

Review of cutaneous metastases from internal malignancies: a 20-year review from a regional cancer treatment centre.

Clinical and experimental dermatology·2021
Same author

First degree hotspots for OMFS recruitment 1967-2010: dental and medical schools where OMFS specialists and trainees were more likely to start their careers.

The British journal of oral & maxillofacial surgery·2020
Same author

Patients', family members' and healthcare practitioners' experiences of Stevens-Johnson syndrome and toxic epidermal necrolysis: a qualitative descriptive study using emotional touchpoints.

Journal of the European Academy of Dermatology and Venereology : JEADV·2020
Same author

Radiation dose tracking in computed tomography: Red alerts and feedback. Implementing a radiation dose alert system in CT.

Radiography (London, England : 1995)·2020
Same author

Management of anal intraepithelial neoplasia and anal squamous cell carcinoma at a tertiary referral centre with a dedicated infectious diseases unit: an 18-year review.

International journal of colorectal disease·2020
Same journal

Unlocking the potential of electronic health records for research purposes.

Irish medical journal·2026
Same journal

ICU Handover: A Persistent Vulnerability in Critical Care Settings.

Irish medical journal·2026
Same journal

The Sugar-Sweetened Beverage Tax (Sugar Tax): Innovation and Stasis.

Irish medical journal·2026
Same journal

Gastrointestinal trichobezoars presenting as abdominal pain and obstruction - Rapunzel syndrome.

Irish medical journal·2026
Same journal

When Sepsis Kills: A Fatal Cascade of Invasive Group A Streptococcal Sepsis.

Irish medical journal·2026
Same journal

Fulminant Thrombotic Thrombocytopenic Purpura presenting through the FAST Stroke Pathway.

Irish medical journal·2026
See all related articles

Related Experiment Video

Updated: Jun 8, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
04:44

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

Nephrogenic systemic fibrosis.

C Kennedy1, C Magee, E Eltayeb

  • 1Department of Nephrology, Beaumont Hospital, Beaumont, Dublin 9. kennedyclaire@gmail.com

Irish Medical Journal
|September 18, 2010
PubMed
Summary
This summary is machine-generated.

Nephrogenic systemic fibrosis (NSF) is a rare but severe skin condition in patients with advanced kidney failure. Irish data shows three NSF cases, all linked to gadolinium exposure, highlighting the need for caution in high-risk patients.

More Related Videos

Induction of Nephrotic Syndrome in Mice by Retrobulbar Injection of Doxorubicin and Prevention of Volume Retention by Sustained Release Aprotinin
07:38

Induction of Nephrotic Syndrome in Mice by Retrobulbar Injection of Doxorubicin and Prevention of Volume Retention by Sustained Release Aprotinin

Published on: May 6, 2018

Related Experiment Videos

Last Updated: Jun 8, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
04:44

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

Induction of Nephrotic Syndrome in Mice by Retrobulbar Injection of Doxorubicin and Prevention of Volume Retention by Sustained Release Aprotinin
07:38

Induction of Nephrotic Syndrome in Mice by Retrobulbar Injection of Doxorubicin and Prevention of Volume Retention by Sustained Release Aprotinin

Published on: May 6, 2018

Area of Science:

  • Nephrology
  • Dermatology
  • Radiology

Background:

  • Nephrogenic systemic fibrosis (NSF) is a debilitating condition exclusively affecting patients with advanced renal failure.
  • Limited data exists on the epidemiology and outcomes of NSF within the Irish population.
  • International reports necessitate a localized examination of NSF prevalence and characteristics.

Observation:

  • A retrospective chart review identified three cases of NSF among 1915 dialysis patients in Ireland.
  • This represents a point prevalence of 0.002 among Irish end-stage kidney disease patients.
  • Significant gadolinium chelate exposure was noted in all three identified NSF cases.

Findings:

  • The study reveals a low point prevalence of NSF in Ireland (0.002).
  • Disease severity varied considerably among the three reported cases.
  • A strong association between gadolinium chelate administration and NSF development was observed.

Implications:

  • Findings underscore the critical need for vigilance regarding gadolinium administration in patients with advanced renal failure.
  • This study contributes essential epidemiological data on NSF specific to Ireland.
  • Recommendations for cautious gadolinium use in at-risk populations are reinforced.