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Updated: Jun 8, 2026

04:23
A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
Published on: April 28, 2019
[Influenza-associated encephalopathy]
Tatsuharu Sato1, Hiroyuki Moriuchi
1Department of Pediatrics, Nagasaki University Hospital.
Nihon Rinsho. Japanese Journal of Clinical Medicine
|September 18, 2010
Summary
Acute encephalopathy, a severe complication of pediatric viral infections like influenza, involves rapid brain damage. This review compares pandemic AH1N1 flu-associated encephalopathy with seasonal flu-associated cases.
Area of Science:
- Neurology
- Infectious Diseases
- Pediatrics
Context:
- Acute encephalopathy is a critical complication of pediatric viral infections, particularly influenza.
- It presents as rapid brain damage without direct viral invasion or inflammation.
- Recent classifications categorize it based on clinical and pathogenic features.
Purpose:
- To review the general pathogenesis and classification of acute encephalopathy.
- To compare the epidemiological, clinical, and pathological features of pandemic AH1N1 flu-associated encephalopathy (FAE) with seasonal FAE.
Summary:
- The 2009 AH1N1 influenza pandemic saw numerous reports of acute encephalopathy globally.
- This article provides a comprehensive overview of acute encephalopathy.
- It specifically contrasts pandemic FAE with seasonal FAE, highlighting key differences.
Impact:
- Enhances understanding of influenza-associated encephalopathy, crucial for pediatric critical care.
- Provides insights into the specific characteristics of pandemic versus seasonal influenza complications.
- Informs clinical management and research directions for acute encephalopathy in children.
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