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Sensitization to Dermatophagoides, Blomia tropicalis, and other mites in atopic patients

Kobi Sade1, Daniel Roitman, Shmuel Kivity

  • 1Allergy and Asthma Center, Tel Aviv Sourasky Medical Center, and Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel. kobisade@gmail.com

The Journal of Asthma : Official Journal of the Association for the Care of Asthma
|September 18, 2010
PubMed
Abstract

Insights

Most Israeli patients with allergic rhinitis are sensitized to house dust mites (HDMs). Dermatophagoides farinae, Dermatophagoides pteronyssinus, and Blomia tropicalis were the most common allergens, highlighting their importance in respiratory diseases.

Area of Science:

  • Allergy and Immunology
  • Environmental Health
  • Epidemiology

Background:

  • House dust mites (HDMs) are significant triggers for persistent allergic conditions like asthma and rhinitis.
  • Diverse HDM species are prevalent in household dust globally, including in Israel.

Purpose of the Study:

  • To determine the prevalence of sensitization to various HDMs.
  • To assess sensitization in patients diagnosed with perennial allergic rhinitis and asthma.

Main Methods:

  • A skin prick test (SPT) was performed on 117 patients with persistent rhinitis at an allergy center in Tel Aviv, Israel.
  • Standardized allergenic extracts of nine mite species were used: Dermatophagoides farinae (DF), Dermatophagoides pteronyssinus (DP), Lepidoglyphus destructor (LD), Blomia tropicalis (BT), Tyrophagus putrescentiae (TP), Acarus siro (AS), Glycyphagus domesticus (GD), Blomia kulagini (BK), and Tetranychus urticae (TU).

Main Results:

  • 81% of patients (95/117) showed positive SPT reactions to at least one mite allergen.
  • The most frequent sensitizations were to DF (78%), DP (75%), and unexpectedly, BT (77%).
  • Sensitization to DF and DP showed a strong correlation (r = .78), while correlations with BT were moderate (r = .60).

Conclusions:

  • This study identifies common mite allergens in Israeli patients with allergic rhinitis, emphasizing BT's significance.
  • These findings suggest that mite extracts can improve diagnosis and treatment for mite-induced respiratory allergies in Israel and similar climates.

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