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Related Experiment Video

Updated: Jun 8, 2026

An Ex vivo Model to Study Hormone Action in the Human Breast

An Ex vivo Model to Study Hormone Action in the Human Breast

Published on: January 8, 2015

"Breast is best": The evidence.

Michael S Kramer¹

¹Department of Pediatrics, McGill University, Canada. michael.kramer@mcgill.ca

Early Human Development

|September 18, 2010

Summary

Breastfeeding promotion interventions show potential for long-term health benefits, including improved neurocognitive development and reduced risks of certain diseases. This study provides key findings from a large trial on breastfeeding

Area of Science:

Pediatrics
Public Health
Developmental Psychology

Background:

Established benefits of breastfeeding include reduced infant morbidity and mortality from infections and necrotizing enterocolitis.
Long-term health effects of breastfeeding, such as protection against obesity, diabetes, and atopic diseases, remain debated due to conflicting evidence.
Neurocognitive development is often associated with breastfeeding, but confounding factors related to maternal characteristics persist.

Purpose of the Study:

To evaluate the long-term health and developmental outcomes of a breastfeeding promotion intervention.
To address the controversy surrounding the 'programming' effects of breastfeeding on child health.
To present findings from a large-scale, cluster-randomized trial on breastfeeding interventions.

Main Methods:

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Changes in Mammary Gland Morphology and Breast Cancer Risk in Rats

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Changes in Mammary Gland Morphology and Breast Cancer Risk in Rats

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Published on: October 16, 2010

A large, cluster-randomized trial was conducted in the Republic of Belarus.
The study employed an intention-to-treat analysis to assess outcomes.
Focus was on a breastfeeding promotion intervention and its impact on longer-term health and developmental markers.

Main Results:

The experimental design and intention-to-treat analysis yielded significant findings.
Results bear on several longer-term health and developmental outcomes associated with breastfeeding.
Specific findings regarding neurocognitive development and disease prevention are detailed.

Conclusions:

The breastfeeding promotion intervention demonstrated important effects on longer-term health and development.
The study's robust design helps mitigate confounding factors in assessing breastfeeding outcomes.
Findings contribute to understanding the lasting impact of breastfeeding on child well-being.