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ArrayTrack: a free FDA bioinformatics tool to support emerging biomedical research--an update
Joshua Xu1, Reagan Kelly, Hong Fang
1Z-Tech Corporation, an ICF International Company at the National Center for Toxicological Research, US Food and Drug Administration, 3900 NCTR Rd, Jefferson, AR 72079, USA. Zhihua.xu@fda.hhs.gov
Human Genomics
|September 18, 2010
Summary
ArrayTrack, a bioinformatics tool from the Food and Drug Administration (FDA), supports genomics, proteomics, and metabolomics data analysis. Recent enhancements enable broader applications in genetics and pathogen genomics research.
Area of Science:
- Bioinformatics
- Genomics
- Proteomics
- Metabolomics
Background:
- ArrayTrack is a widely adopted FDA bioinformatics tool for genomics.
- It offers integrated data management, analysis, and interpretation for microarray data.
- Its functionalities extend to other molecular technologies.
Purpose of the Study:
- To review the key functionalities of ArrayTrack.
- To highlight recent extensions supporting evolving FDA research programs.
- To showcase ArrayTrack's adaptability to new data types and research areas.
Main Methods:
- Review of ArrayTrack's existing and newly developed features.
- Assessment of its application to diverse molecular data (genomics, proteomics, metabolomics).
- Integration of annotation data for genetics and pathogen studies.
Main Results:
- ArrayTrack now manages, analyzes, and interprets proteomics and metabolomics data.
- It integrates single nucleotide polymorphism (SNP) and quantitative trait loci (QTL) annotation.
- Capabilities for bacterial food-borne pathogen genomics data analysis have been added.
Conclusions:
- ArrayTrack has evolved significantly since 2001.
- The tool supports a wider range of molecular data and research needs.
- It remains a valuable asset for bioinformatics research at the FDA and beyond.
