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Updated: Jun 8, 2026

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
Published on: December 11, 2017
Quality-of-life in octogenarians one year after aortic valve replacement with or without coronary artery bypass
Sandra Folkmann1, Michael Gorlitzer, Gabriel Weiss
1Department of Cardiac Surgery, Hospital Hietzing, Wolkersbergenstr. 1, 1130 Vienna, Austria. s.folkmann@gmx.at
Insights
Open aortic valve replacement (AVR) in octogenarians shows an 81.8% one-year survival rate. Quality of life significantly improves post-surgery, supporting AVR for elderly patients.
Area of Science:
- Cardiology
- Cardiac Surgery
- Geriatric Medicine
Background:
- The rise of minimally invasive percutaneous aortic valve replacement necessitates re-evaluation of outcomes for traditional open aortic valve replacement (AVR).
- Octogenarians represent a growing patient demographic undergoing AVR, with unique considerations for surgical risk and recovery.
Purpose of the Study:
- To evaluate one-year survival rates and quality of life (QoL) after open bioprosthetic AVR in octogenarians.
- To compare outcomes between AVR with and without concomitant coronary artery bypass grafting (CABG).
- To identify risk factors influencing mortality in this elderly population.
Main Methods:
- Retrospective review of 154 octogenarian patients (mean age 82.9 years) who underwent open AVR between 2005-2007.
- Patients were divided into two groups: AVR with CABG (n=80) and AVR without CABG (n=74).
- One-year QoL was assessed using the Seattle Angina Questionnaire; mortality risk factors were analyzed.
Main Results:
- The in-hospital mortality rate was 7.8%, and the 12-month survival rate was 81.8%.
- No significant differences in preoperative risk factors (e.g., renal insufficiency, COPD, diabetes, CVD, logistic EuroSCORE, CABG) were found between survivors and non-survivors.
- A substantial improvement in physical fitness was reported by 126 patients one year post-surgery.
Conclusions:
- Open AVR, particularly without concomitant CABG, is associated with favorable outcomes in octogenarians.
- Significant QoL improvement one year after surgery supports the consideration of AVR for patients over 80.
- Preoperative risk factors did not reliably predict mortality, highlighting the complex interplay of factors in this age group.
Abstract:
The increasing number of interventions for percutaneous aortic valve replacement (AVR) justify a renewed evaluation of one-year survival rates after open AVR with and without coronary artery bypass in octogenarians. Risk factors influencing mortality are compared, and the patients' quality-of-life (QoL) after one year is assessed. One hundred and fifty-four patients (102 females, 52 males) aged on average 82.9±2.5 years, who had undergone open bioprosthetic AVR with (n=80) and without (n=74) coronary artery bypass grafting (CABG) between January 2005 and December 2007 were reviewed retrospectively. Risk factors for mortality were analyzed. The patient's QoL after one year was evaluated by administering the Seattle Angina Questionnaire on the telephone. The mean in-hospital mortality rate was 7.8%. The 12-month survival rate was 81.8%. Preoperative risk factors revealed no difference between survivors and non-survivors: renal insufficiency, chronic obstructive pulmonary disease (COPD), diabetes, cerebrovascular disease (CVD), peripheral vascular disease, logistic EuroSCORE and concomitant CABG. Assessment of QoL revealed a substantial improvement of physical fitness in all 126 patients. Surgery in the aortic valve without CABG is associated with a good outcome. The improvement in QoL after one year supports the decision to operate on patients older than 80 years of age.
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