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Updated: Jun 8, 2026

Application of Lucilia sericata Larvae in Debridement of Pressure Wounds in Outpatient Settings
Published on: December 4, 2021
Debridement of the noninfected wound
Rhonda S Cornell1, Andrew J Meyr, John S Steinberg
1Department of Plastic Surgery, Georgetown University School of Medicine, Washington, DC, USA.
Abstract:
The utility of wound debridement has expanded to include the management of all chronic wounds, even in the absence of infection and gross necrosis. Biofilms, metalloproteases on the wound base, and senescent cells at the wound edge irreversibly change the physiologic features of wound healing and contribute to a pathologic, chronic inflammatory environment. The objective of this review is to provide surgeons with a basic understanding of the processes of debridement in the noninfected wound.
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