Related Experiment Video

Updated: Jun 8, 2026

Bacterial Artificial Chromosomes: A Functional Genomics Tool for the Study of Positive-strand RNA Viruses
12:20

Bacterial Artificial Chromosomes: A Functional Genomics Tool for the Study of Positive-strand RNA Viruses

Published on: December 29, 2015

Measles-related hospitalizations and complications in Japan, 2007-2008

Hideo Yasunaga1, Yongjin Shi, Masato Takeuchi

  • 1Department of Health Management and Policy, Graduate School of Medicine, The University of Tokyo, Tokyo. yasunagah-jyo@h.u-tokyo.ac.jp

Internal Medicine (Tokyo, Japan)
|September 18, 2010
PubMed
Abstract

Insights

Severe measles hospitalization in Japan (2007-2008) primarily affected young children and young adults, with pneumonia being a common complication. Pregnant women experienced adverse outcomes, highlighting the need for continued disease monitoring.

Area of Science:

  • Infectious Diseases
  • Epidemiology
  • Public Health

Background:

  • Measles is a highly contagious viral illness.
  • Severe measles cases necessitate hospitalization, posing a significant public health concern.
  • Understanding clinical features and complications of hospitalized measles patients is crucial for effective management.

Purpose of the Study:

  • To describe the clinical characteristics of severe measles cases requiring hospitalization in Japan.
  • To identify and analyze related complications in hospitalized measles patients.
  • To examine demographic factors, including age, pregnancy, and malignancy, associated with severe measles.

Main Methods:

  • Utilized the Diagnosis Procedure Combination (DPC) inpatient database for patient records from July to December 2007 and 2008.
  • Extracted data on hospitalized patients diagnosed with measles.
  • Analyzed patient demographics, age distribution, and complication rates, including those related to pregnancy and malignancy.

Main Results:

  • A total of 1,037 inpatients were identified across 377 hospitals.
  • Two age peaks were observed: children ≤4 years (21%) and young adults aged 15-29 years (45%).
  • Common complications included pneumonia (8.7%), encephalitis (2.1%), and intestinal issues (0.7%). Pneumonia was more prevalent in younger patients (≤14 years).

Conclusions:

  • The study provides valuable insights into the clinical presentation of severe measles.
  • Hospitalized measles patients, particularly young adults and children, face significant complications like pneumonia.
  • Continued surveillance using the DPC database is essential for tracking measles trends.

More Related Videos

Detection of Polyfunctional T Cells in Children Vaccinated with Japanese Encephalitis Vaccine via the Flow Cytometry Technique09:37

Detection of Polyfunctional T Cells in Children Vaccinated with Japanese Encephalitis Vaccine via the Flow Cytometry Technique

Published on: September 23, 2022

Related Concept Videos

Vaccinations01:51

Vaccinations

Overview
Respiratory Syncytial Virus Disease01:29

Respiratory Syncytial Virus Disease

Human respiratory syncytial virus (RSV) is a widespread pathogen that primarily targets infants and young children but also poses a serious health risk to elderly and immunocompromised individuals. Belonging to the Pneumoviridae family, RSV is a negative-sense, single-stranded RNA virus within the Pneumovirus genus. Its global health burden is significant, with millions of cases annually resulting in hospitalizations and mortality, particularly in resource-limited settings. Although most...
Influenza01:27

Influenza

Influenza is an acute, highly communicable viral disease that affects the respiratory tract and is responsible for seasonal epidemics worldwide. Influenza A is the most prevalent type associated with widespread outbreaks and is subtyped based on two surface glycoproteins: hemagglutinin (H) and neuraminidase (N), as in H1N1. These glycoproteins are essential for viral infectivity, transmission, and immune recognition. Transmission occurs primarily through respiratory droplets and contaminated...
Asthma-III: Symptoms and Complications01:24

Asthma-III: Symptoms and Complications

Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
Diphtheria01:28

Diphtheria

Diphtheria is an acute, toxin-mediated infectious disease that primarily affects the upper respiratory tract. It is caused by Corynebacterium diphtheriae, a Gram-positive, pleomorphic rod that lacks spore-forming capability and exhibits a characteristic club-shaped morphology under microscopic examination. While C. diphtheriae can asymptomatically colonize mucosal surfaces, clinical disease manifests only when the bacterial strain is lysogenized by a specific β-corynephage. This phage...
Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...