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Related Concept Videos

Infectious Diseases and Their Occurrence01:28

Infectious Diseases and Their Occurrence

Infectious diseases appear in populations through various transmission patterns, influenced by pathogen characteristics, population immunity, environmental conditions, and social behavior. Understanding these patterns is essential for effective public health surveillance and intervention. These categories—sporadic, outbreak, epidemic, pandemic, and endemic—help frame the nature and scope of disease events.Sporadic diseases occur irregularly and infrequently, without a predictable temporal or...
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Influenza is an acute, highly communicable viral disease that affects the respiratory tract and is responsible for seasonal epidemics worldwide. Influenza A is the most prevalent type associated with widespread outbreaks and is subtyped based on two surface glycoproteins: hemagglutinin (H) and neuraminidase (N), as in H1N1. These glycoproteins are essential for viral infectivity, transmission, and immune recognition. Transmission occurs primarily through respiratory droplets and contaminated...
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Related Experiment Video

Updated: Jun 8, 2026

Production of High-Titer Infectious Influenza Pseudotyped Particles with Envelope Glycoproteins from Highly Pathogenic H5N1 and Avian H7N9 Viruses
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Published on: January 15, 2020

H1N1pdm in the Americas.

Justin Lessler1, Thais Dos Santos2, Ximena Aguilera2

  • 1Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe St. Baltimore, MD 21205, USA.

Epidemics
|September 18, 2010
PubMed
Summary

The 2009 pandemic influenza A (H1N1pdm) virus showed seasonal transmission patterns in the Americas. Latitude was the strongest factor associated with H1N1pdm spread, suggesting climate and behavior influences.

Keywords:
influenzapandemic H1N1reproductive numberseasonality

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Area of Science:

  • Epidemiology
  • Virology
  • Public Health

Background:

  • The 2009 pandemic influenza A (H1N1pdm) virus emerged in late April 2009.
  • Confirmed cases were reported to the Pan American Health Organization (PAHO) from April 26 to July 18, 2009.

Purpose of the Study:

  • To characterize the early spread of the H1N1 pandemic in the Americas.
  • To examine the variation in H1N1pdm transmission by season.

Main Methods:

  • Utilized PAHO member state reports from April 26 to July 18, 2009.
  • Estimated the reproductive number (R) for H1N1pdm in a sample of member states.
  • Assessed the association between R estimates and latitude, temperature, humidity, and population age structure.

Main Results:

  • Peak reproductive number estimates for H1N1pdm ranged from 1.3 to 2.1.
  • Reproductive number estimates were most strongly associated with latitude.
  • Latitude's association suggests a significant seasonal component to H1N1pdm transmission.

Conclusions:

  • The early spread of H1N1pdm in the Americas exhibited a strong seasonal component.
  • Latitude, likely as a proxy for seasonal climate and behavioral changes, was the primary driver of this seasonality.
  • The precise mechanisms underlying H1N1pdm seasonality require further investigation.