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Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model

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Bowel perforation after pediatric living donor liver transplantation

Yukihiro Sanada¹, Koichi Mizuta, Taiichi Wakiya

¹Department of Transplant Surgery, Jichi Medical University, Tochigi, 329-0498, Japan. yuki371@jichi.ac.jp

Pediatric Surgery International

|September 18, 2010

Abstract

Purpose:

Bowel perforation after liver transplantation (LT) is a rare, but highly lethal complication with a poor prognosis. Here, we report the outcome of cases of bowel perforation after pediatric LT in our department.

Patients And Methods:

The study subjects were 148 patients who underwent pediatric living donor liver transplantation. The 114 with biliary atresia (BA) were divided into two groups: those with associated bowel perforation (Group A) and those without (Group B).

Results:

Four patients in all (2.5%) suffered bowel perforation. Their original disease was BA and emergency surgery was performed in all cases, with a mortality rate of 50.0%. Comparison of Groups A and B revealed significant differences in the patient age, body weight, duration of surgery, cold ischemic time, and blood loss volume. The survival rates in Groups A and B were 50.0 and 99.1%, respectively (p < 0.01). Duration of surgery was an independent risk factor (p = 0.05).

Conclusion:

Bowel perforation after LT is a potentially fatal complication. LT is a procedure that requires care and precision, and the possibility of bowel perforation should always be borne in mind during post-operative management, when the duration of surgery has been long.

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