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Updated: Jun 8, 2026

Isolation and Culture of Post-Natal Mouse Cerebellar Granule Neuron Progenitor Cells and Neurons
Published on: January 16, 2009
Put them out to pasture? What are old granule cells good for, anyway...?
James B Aimone1, Wei Deng, Fred H Gage
1Laboratory of Genetics, The Salk Institute for Biological Studies, La Jolla, California 92037, USA. aimone@salk.edu
Abstract:
In this issue, Alme and colleagues propose a novel hypothesis that young adult-born neurons represent the functional population of the dentate gyrus, and that old granule cells "retire" from relevance. Here, we present several implications of this interesting theory for the function of both neurogenesis and the dentate gyrus.
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