Related Experiment Video
Updated: Jun 8, 2026

Antibody Transfection into Neurons as a Tool to Study Disease Pathogenesis
Published on: September 26, 2012
Molecular mimicry in human diseases--phenomena or epiphenomena?
Sourya Acharya1, Samarth Shukla, S N Mahajan
1Dept. of Medicine, Dutta Meghe Institute of Medical Sciences, J. N. Medical College, Sawangi (Meghe), Wardha - 442004, Maharashtra.
Abstract:
Molecular mimicry is one mechanism by which infectious agents (or other exogenous substances) trigger an immune response against the host antigens. When a susceptible host acquires an infection with an organism that has antigens immunologically similar to the host antigens but differ sufficiently, to induce, an immune response when presented to T cells, results in loss of tolerance to host antigens. Further more there is development of a pathogen-specific immune response that cross-reacts with host structures to cause tissue damage and disease. Till date the advances in the research in molecular biology has documented evidence to suggest that molecular mimicry plays in important role in pathogenesis of a number of diseases. This review is a brief overview of some of these disorders.
Related Concept Videos
Nonconscious Mimicry
Antigens Involved in Adaptive Immunity
Complete Antigens
Complete antigens possess both immunogenicity and reactivity.
Cross-reactivity
Introduction to Language of Pathophysiology l
Epistasis Analysis
Malaria

