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Updated: Jun 8, 2026

Determination of Reproductive Competence by Confirming Pubertal Onset and Performing a Fertility Assay in Mice and Rats
Published on: October 13, 2018
Late onset hypogonadism, sexuality and fertility
Kevan Wylie1, Natalie Froggatt
1University of Sheffield, Royal Hallamshire Hospital, Sheffield, UK. k.r.wylie@sheffield.ac.uk
Abstract:
The numerous and varying effects of androgen deficiency in males cause an array of symptoms and complaints any of which can be the trigger for a medical consultation. It is, therefore, important to consider the possibility of late onset hypogonadism (LOH) in a patient who is presenting with any such symptoms. This review describes LOH and the current guidelines for its treatment and management. Also discussed are the normal changes undergone by men as they age and the effects that are expected due to this change. The relationship between LOH and its effects on both sexuality and fertility are also considered.
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