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Near-Infrared Temperature Measurement Technique for Water Surrounding an Induction-heated Small Magnetic Sphere
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Published on: April 30, 2018

Absolute temperature imaging using intermolecular multiple quantum MRI.

Elizabeth R Jenista1, Rosa T Branca, Warren S Warren

  • 1Department of Chemistry, Duke University, Durham, North Carolina, USA. elizabeth.specht@duke.edu

International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group
|September 21, 2010
PubMed
Summary
This summary is machine-generated.

Intermolecular multiple quantum coherences (iMQCs) offer artifact-free MRI temperature imaging, particularly for fatty tissues like the breast. This method provides absolute temperature maps, overcoming limitations of other techniques.

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Area of Science:

  • Magnetic Resonance Imaging (MRI)
  • Biomedical Engineering
  • Medical Physics

Background:

  • Conventional MRI thermometry methods face artifacts from susceptibility changes and magnetic field inhomogeneities.
  • Fatty tissues present unique challenges for temperature imaging due to susceptibility variations.

Purpose of the Study:

  • To review MRI temperature imaging methods utilizing intermolecular multiple quantum coherences (iMQCs).
  • To explore the theoretical background and adaptations of iMQCs for temperature imaging.
  • To highlight the potential of iMQCs in high-fat tissues.

Main Methods:

  • Review of existing studies on iMQC temperature imaging.
  • Experiments conducted at 7 Tesla (7T) field strength.
  • Utilized phantoms (cream) and in vivo models (obese mice).

Main Results:

  • iMQC-based thermometry can generate absolute temperature maps.
  • This technique circumvents artifacts caused by susceptibility and magnetic field inhomogeneities.
  • Demonstrated in vivo temperature mapping in animal models.

Conclusions:

  • iMQC-based temperature imaging shows significant promise for applications in fatty tissues, such as breast imaging.
  • It offers a viable alternative to standard proton frequency shift methods, which are challenged by fat's susceptibility changes.
  • The reliance on fat signal as an internal reference enhances its applicability in specific tissues.