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Updated: Jun 8, 2026

Fabrication of Carbon Nanotube High-Frequency Nanoelectronic Biosensor for Sensing in High Ionic Strength Solutions
Published on: July 22, 2013
Noncovalently functionalized multi-wall carbon nanotubes in aqueous solution using the hydrophobin HFBI and their
Xinsheng Wang1, Huicai Wang, Yujian Huang
1The Key Laboratory of Bioactive Materials, Ministry of Education, College of Life Sciences, Nankai University, Weijin Road No. 94, Tianjin 300071, PR China.
Abstract:
A novel noncovalent approach was developed for the functionalization of multi-wall carbon nanotubes (MWNTs) using the hydrophobin, HFBI. Owing to the amphipathic nature, HFBI can be adopted onto the surface of MWNTs to form HFBI-MWNTs nanocomposite with good dispersion in water. The HFBI-MWNTs nanocomposite was characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM) and water contact angle measurements (WCA). Furthermore, a glucose biosensor was developed based on HFBI-MWNTs by a one-step casting method. The resulting biosensor displayed high sensitivity, wider linear range, low detection limit, and fast response for glucose detection, which implicated that the HFBI-MWNTs nanocomposite film holds great promise in the design of electrochemical devices, such as sensors and biosensors.
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