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Published on: June 23, 2012
Genetic analysis of the SNPforID 34-plex ancestry informative SNP panel in Tunisian and Libyan populations
H Khodjet-el-Khil1, K Fadhlaoui-Zid, L Cherni
1Laboratory of Genetics, Immunology and Human Pathology, Faculty of Sciences of Tunis, El Manar University, Manar I, 1060 Tunis, Tunisia. housseinkek@yahoo.fr
Abstract:
A total of 149 unrelated and healthy individuals comprising: Tunisian Berbers, Tunisians with Andalusian origin and Libyans were typed with the SNPforID 34-plex ancestry informative marker (AIM) SNP panel. Results of 31 of the 34 SNPs are presented and no deviations from Hardy-Weinberg equilibrium were observed after Bonferroni correction (p=0.00161) except rs722098 (p=0.0000). Comparisons of allele frequencies showed high divergence values between North Africans and Europeans (δ>30%) in markers: rs4540055 (allele A) and rs16891982. Our study adds data that can be used as training set genotypes for future ancestry investigations in forensic cases and suggests these AIM-SNPs can successfully differentiate North Africans and Mediterranean Europeans.
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