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Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis

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[Neurological soft signs in pervasive developmental disorders].

S Halayem¹, A Bouden, M B Halayem

¹Service de Pédopsychiatrie, Hôpital Razi, rue des Orangers, 2010 La-Manouba, Tunisie. soumeyyadhouib@yahoo.fr

|September 21, 2010

Summary

Neurological soft signs (NSS) are impaired in children with autism (AD) and Pervasive Developmental Disorder Not Otherwise Specified (PDDNOS). Motor and sensory integration deficits are significant in these children, suggesting motor control issues are part of autism spectrum disorders.

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Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale

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Published on: August 25, 2014

Area of Science:

Neurodevelopmental disorders
Pediatric neurology
Autism spectrum disorders

Context:

Limited research exists on the full spectrum of neurological soft signs (NSS) in children with Pervasive Developmental Disorder (PDD), particularly PDD Not Otherwise Specified (PDDNOS).
Previous studies often focused on specific motor signs in autism and Asperger's syndrome.

Purpose:

To compare the performance of children with autistic disorder (AD) and PDDNOS on a comprehensive scale of NSS.
To investigate the association between NSS severity and autism symptom severity using diagnostic and symptom rating scales.
To explore the relationship between NSS and cognitive function in children with autism spectrum disorders.

Summary:

Children with AD and PDDNOS exhibited significant differences in motor integration and sensory integration functions compared to controls.
PDDNOS group showed significantly higher total NSS scores, including motor coordination, motor integration, sensory integration, and abnormal movements.
Lower motor coordination skills in the AD group correlated with higher communication scores on the Autism Diagnostic Interview-Revised (ADI-R).

Impact:

This study confirms impaired neurological functioning in children with autism and PDDNOS.
Findings support the inclusion of motor control problems within the spectrum of autism spectrum disorders.
The lack of correlation between NSS and intellectual aptitude offers new insights into the neurodevelopmental models of autism.