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Related Experiment Video

Updated: Jun 8, 2026

Optical Frequency Domain Imaging of Ex vivo Pulmonary Resection Specimens: Obtaining One to One Image to Histopathology Correlation

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Published on: January 22, 2013

New clinically applicable method for visualizing adjacent lung segments using an infrared thoracoscopy system.

Noriyuki Misaki¹, Sung Soo Chang, Hitoshi Igai

¹Department of General Thoracic Surgery, Breast and Endocrinological Surgery, Faculty of Medicine, Kagawa University, Japan. nmisaki@med.kagawa-u.ac.jp

The Journal of Thoracic and Cardiovascular Surgery

|September 21, 2010

Summary

Infrared thoracoscopy with indocyanine green safely identifies lung segments for surgery. This technique aids precise segmentectomy, especially in challenging cases like emphysema or limited surgical views.

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Area of Science:

Thoracic Surgery
Surgical Imaging
Pulmonology

Background:

Accurate identification of lung segments is crucial for effective segmentectomy.
Traditional methods can be challenging, particularly in cases with compromised lung function or limited visualization.
Minimally invasive thoracic surgery requires precise anatomical guidance.

Purpose of the Study:

To evaluate the feasibility of using infrared thoracoscopy with indocyanine green for lung segment identification during segmentectomy.
To assess the safety and efficacy of this imaging technique in a clinical setting.

Main Methods:

A clinical trial involving 8 patients undergoing segmentectomy for various lung lesions.
Intravenous injection of indocyanine green followed by observation with an infrared thoracoscopy system.
Identification and electrocautery marking of the target lung segment based on observed color changes.

Main Results:

Successful identification of target lung segments in all patients, with clear color zonation observed.
Normal lung tissue stained blue within 13 seconds post-injection, with peak intensity at 28 seconds.
No complications related to the infrared thoracoscopy or indocyanine green injection were reported.

Conclusions:

Infrared thoracoscopy with indocyanine green provides a rapid and easy method for identifying lung segments for segmentectomy.
This technique is particularly beneficial for patients with severe emphysema or when surgical views are limited.
The method enhances precision in minimally invasive thoracic procedures.