Cutaneous angiomyxoma and pilomatricoma: a new combination

Superficial angiomyxomas are rare benign tumors that typically present as a solitary lesion or as a component of Carney complex and rarely have been associated with other lesions. In this article, we report 3 cases of an unusual association of superficial angiomyxoma with pilomatricoma. This combination has never been described in the literature. The 3 patients presented with variable-sized pedunculated, asymptomatic skin papules overlying firm deeply situated nodules. Histopathologic examination demonstrated that the superficial pedunculated lesion is a superficial angimyxoma with underlying pilomatricoma. Thorough clinical examination failed to reveal any further lesions. We present a rare and unique combination of angiomyxoma and pilomatricoma. This combination may be incidental, representing collision tumors or etiologically related.