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Infectious causes for feline upper respiratory tract disease--a case-control study
Bodil Ström Holst1, Sofia Hanås, Louise T Berndtsson
1SLU, Department of Clinical Sciences, Box 7054, SE-750 07 Uppsala, Sweden. bodil.strom-holst@kv.slu.se
Journal of Feline Medicine and Surgery
|September 21, 2010
Summary
Mycoplasma felis was significantly more prevalent in cat groups with upper respiratory tract disease (URTD). This finding suggests M. felis is associated with URTD in group-living felines.
Area of Science:
- Veterinary Medicine
- Microbiology
- Infectious Diseases
Background:
- Upper respiratory tract disease (URTD) is common in group-living cats.
- Identifying causative agents is crucial for effective management and prevention.
Purpose of the Study:
- To investigate the prevalence of specific microorganisms in cats with URTD, in-contact cats, and control groups.
- To determine the association between identified agents and clinical signs of URTD.
Main Methods:
- Case-control study design.
- Sampling from conjunctival fornix and oropharynx.
- Real-time PCR for feline herpesvirus-1 (FHV), Mycoplasma felis, and Chlamydiaceae.
- Bacteriological culture and viral isolation for oropharyngeal samples.
Main Results:
- Specific infectious agents were identified in 55% of case households and 7.5% of cats.
- Mycoplasma felis and Chlamydiae were detected only in case households.
- A statistically significant difference in M. felis prevalence was found between case and control households (P=0.047).
Conclusions:
- Mycoplasma felis prevalence is significantly associated with clinical signs of URTD in group-living cats.
- The study highlights M. felis as a potential key pathogen in feline URTD outbreaks.
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