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Related Concept Videos

Pulmonary Embolism I: Introduction01:29

Pulmonary Embolism I: Introduction

Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
Pulmonary Embolism I: Introduction01:19

Pulmonary Embolism I: Introduction

A blood clot, or thrombus, is a semi-solid mass composed of fibrin, platelets, and red blood cells. When it forms within a vessel, it can obstruct blood flow, known as thrombosis. If part of the clot detaches, it becomes an embolus that can travel and block distant vessels. When this occurs in the pulmonary arteries, it causes a condition known as pulmonary embolism (PE).Origin and ImpactMost often, the embolus originates from a thrombus in the deep veins of the lower limbs, a condition called...
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
Pulmonary Embolism III: Nursing Management01:27

Pulmonary Embolism III: Nursing Management

A pulmonary embolism occurs when a thrombus, amniotic fluid, tumor tissue, fat, or air embolus blocks one or more pulmonary arteries. Effective nursing management and patient education are crucial for improving outcomes and preventing recurrence.Nursing management starts with obtaining a comprehensive patient history, particularly noting any history of deep vein thrombosis (DVT). Assess for clinical manifestations, including dyspnea, chest pain, crackles, heart murmurs, and signs of right-sided...
Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...

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Related Experiment Video

Updated: Jun 8, 2026

Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet
09:22

Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet

Published on: November 4, 2015

Multiple pulmonary thromboembolism and severe depression.

Panagiotis Ferentinos1, Emmanouil Rizos, Christos Christodoulou

  • 12nd Department of Psychiatry, ATTIKON University Hospital, National and Kapodistrian University of Athens, 12462 Athens, Greece. pferentinos@med.uoa.gr

General Hospital Psychiatry
|September 21, 2010
PubMed
Summary

Pulmonary embolism, a cardiovascular condition, can trigger severe depression. This case report suggests a bidirectional link between major depression and pulmonary thromboembolism, similar to heart attack

Related Experiment Videos

Last Updated: Jun 8, 2026

Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet
09:22

Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet

Published on: November 4, 2015

Area of Science:

  • Cardiology
  • Psychiatry
  • Oncology

Background:

  • Major depression and cardiovascular disease share a known bidirectional relationship.
  • Severe depression can be a risk factor for pulmonary embolism, but the reverse is less understood.
  • The vascular depression hypothesis links cardiovascular events to depression via cerebral damage.

Purpose of the Study:

  • To report a case of pulmonary thromboembolism associated with new-onset depression.
  • To explore the potential bidirectional relationship between pulmonary thromboembolism and major depression.

Main Methods:

  • Case report of a 61-year-old male patient.
  • Diagnosis of multiple pulmonary thromboembolism attributed to intraluminal sarcoma.
  • Observation of severe melancholic depression onset and remission with venlafaxine treatment.

Main Results:

  • A rare case of pulmonary artery sarcoma causing multiple pulmonary thromboembolism was identified.
  • The patient developed severe depression which resolved with antidepressant medication.
  • This suggests a potential link between pulmonary thromboembolism and depression.

Conclusions:

  • Multiple pulmonary thromboembolism may have a bidirectional relationship with major depression.
  • Pathophysiological mechanisms may involve cerebral damage from hypoxia or inflammation, supporting the vascular depression hypothesis.
  • This relationship mirrors that observed between myocardial infarction and depression.