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Related Concept Videos

Depression: Overview01:18

Depression: Overview

Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
Long-term Depression01:05

Long-term Depression

Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Long-term Depression01:03

Long-term Depression

Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Calcium Ion Concentration Mechanism
If over time, all...

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Related Experiment Video

Updated: Jun 8, 2026

Individualized rTMS Treatment for Depression using an fMRI-Based Targeting Method
07:12

Individualized rTMS Treatment for Depression using an fMRI-Based Targeting Method

Published on: August 2, 2021

Identifying tumor patients' depression.

Susanne Singer1, Anna Brown, Jens Einenkel

  • 1Department of Medical Psychology and Medical Sociology, University of Leipzig, Leipzig, Germany. susanne.singer@medizin.uni-leipzig.de

Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer
|September 21, 2010
PubMed
Summary
This summary is machine-generated.

The Hospital Anxiety and Depression Scale (HADS) effectively identifies depression in cancer patients. Healthcare providers, including doctors and nurses, were less accurate in detecting depression among these patients.

Related Experiment Videos

Last Updated: Jun 8, 2026

Individualized rTMS Treatment for Depression using an fMRI-Based Targeting Method
07:12

Individualized rTMS Treatment for Depression using an fMRI-Based Targeting Method

Published on: August 2, 2021

Area of Science:

  • Oncology
  • Psychiatry
  • Clinical Psychology

Background:

  • Depression is a common comorbidity in cancer patients, significantly impacting treatment outcomes and quality of life.
  • Accurate and timely detection of depression is crucial for effective management in oncological care.

Purpose of the Study:

  • To compare the diagnostic precision of the Hospital Anxiety and Depression Scale (HADS) against assessments by physicians and nurses for detecting clinical depression in tumor patients.
  • To evaluate the effectiveness of a screening questionnaire versus clinician-based assessment in an inpatient cancer setting.

Main Methods:

  • A cohort of 329 inpatient tumor patients undergoing initial cancer treatment were assessed.
  • Diagnosis of depression was established using the Structured Clinical Interview for DSM (SCID).
  • Patients completed the HADS; physicians and nurses provided independent mental health assessments.

Main Results:

  • The HADS demonstrated high sensitivity (0.96) and good specificity (0.50) in identifying depressed patients.
  • Physicians identified 54% of depressed patients (sensitivity) with 38% specificity.
  • Nurses identified 68% of depressed patients (sensitivity) with 45% specificity.

Conclusions:

  • The HADS is a highly effective tool for screening depression in acute oncological care settings.
  • Physicians and nurses frequently underestimated or missed depression in cancer patients.
  • Implementing validated screening tools like HADS is recommended for improved mental health care in oncology.