Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Stem Cell Culture

Stem Cell Culture

Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...

Stem Cell Therapy for Tissue Regeneration

Stem Cell Therapy for Tissue Regeneration

Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...

Embryonic Stem Cells

Embryonic Stem Cells

Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.

Embryonic Stem Cells

Embryonic Stem Cells

Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...

Adult Stem Cells

Adult Stem Cells

Stem cells are undifferentiated cells that divide and produce more stem cells or progenitor cells that differentiate into mature, specialized cell types. All the cells in the body are generated from stem cells in the early embryo, but small populations of stem cells are also present in many adult tissues including the bone marrow, brain, skin, and gut. These adult stem cells typically produce the various cell types found in that tissue—to replace cells that are damaged or to continuously renew...

Regulation of Hematopoietic Stem Cells

Regulation of Hematopoietic Stem Cells

All blood and immune cells are produced from the multipotent hematopoietic stem cells (HSCs) by the process of hematopoiesis. However, they all have a limited life span. In addition, many are depleted in immune surveillance or combatting an injury or infection. This makes blood one of the most regenerative tissues. Hematopoiesis helps replenish these blood and immune cells, restoring the body's normal functioning. However, overproduction of blood and immune cells can make them cancerous or...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

German Translation and Validation of the Standardized Cosmesis and Health Nasal Outcomes Survey Questionnaire.

Facial plastic surgery : FPS·2026

Same author

Revision Rhinoplasty: Technique and Updates in Evidence.

Facial plastic surgery clinics of North America·2026

Same author

Dorsal Preservation versus Conventional Hump Reduction Rhinoplasty: A Seven-Year Review of Patient Reported Outcomes and Concurrent Operative Techniques.

Plastic and reconstructive surgery·2026

Same author

Understanding Perceived Forehead Changes Post-Endoscopic Brow Lift: The Impact of Frontalis Muscle Contraction.

Plastic and reconstructive surgery·2026

Same author

Features of Importance in the Nasal Exam in Rhinoplasty.

Facial plastic surgery & aesthetic medicine·2026

Same author

Quantitative Analysis of Upper Eyelid Volume Changes in East Asian Patients Following Double Eyelid Surgery Using 3-Dimensional Stereophotogrammetry.

The Journal of craniofacial surgery·2026

Search research articles

Related Experiment Video

Updated: Jun 8, 2026

Isolation of Early Hematopoietic Stem Cells from Murine Yolk Sac and AGM

Isolation of Early Hematopoietic Stem Cells from Murine Yolk Sac and AGM

Published on: June 27, 2008

An introduction to stem cell biology.

Shirin Hemmat¹, David M Lieberman, Sam P Most

¹Division of Facial Plastic and Reconstructive Surgery, Stanford University School of Medicine, Stanford, California, USA.

Facial Plastic Surgery : FPS

|September 21, 2010

Summary

Stem cell research has rapidly advanced, offering numerous clinical applications. This review covers stem cell types and somatic cell nuclear transfer for regenerative medicine, particularly in facial plastic surgery.

More Related Videos

Assessing Stem Cell DNA Integrity for Cardiac Cell Therapy

Assessing Stem Cell DNA Integrity for Cardiac Cell Therapy

Published on: January 25, 2019

Enrichment and Purging of Human Embryonic Stem Cells by Detection of Cell Surface Antigens Using the Monoclonal Antibodies TG30 and GCTM-2

Enrichment and Purging of Human Embryonic Stem Cells by Detection of Cell Surface Antigens Using the Monoclonal Antibodies TG30 and GCTM-2

Published on: December 6, 2013

Related Experiment Videos

Last Updated: Jun 8, 2026

Isolation of Early Hematopoietic Stem Cells from Murine Yolk Sac and AGM

Isolation of Early Hematopoietic Stem Cells from Murine Yolk Sac and AGM

Published on: June 27, 2008

Assessing Stem Cell DNA Integrity for Cardiac Cell Therapy

Assessing Stem Cell DNA Integrity for Cardiac Cell Therapy

Published on: January 25, 2019

Enrichment and Purging of Human Embryonic Stem Cells by Detection of Cell Surface Antigens Using the Monoclonal Antibodies TG30 and GCTM-2

Enrichment and Purging of Human Embryonic Stem Cells by Detection of Cell Surface Antigens Using the Monoclonal Antibodies TG30 and GCTM-2

Published on: December 6, 2013

Area of Science:

Stem cell biology and regenerative medicine.

Background:

Stem cell biology has expanded significantly over the last two decades.
Research has rapidly increased understanding of complex stem cells, leading to potential clinical applications.

Purpose of the Study:

To provide an overview of current stem cell research for scientific and medical applications.
To review different stem cell types and somatic cell nuclear transfer technology.
To establish a foundation for understanding stem cell technology in facial plastic and reconstructive surgery.

Main Methods:

Review of existing scientific literature on stem cell biology.
Discussion of various stem cell types: adult, embryonic, and perinatal.
Explanation of somatic cell nuclear transfer (SCNT) for generating totipotent stem cells.

Main Results:

Comprehensive overview of stem cell research advancements.
Detailed description of stem cell classifications and SCNT.
Exploration of stem cell applications in facial plastic and reconstructive surgery.

Conclusions:

Stem cell research offers vast potential for medical and scientific applications.
Somatic cell nuclear transfer provides an alternative to embryonic stem cells.
Understanding stem cell technology is crucial for advancements in facial plastic and reconstructive surgery.